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1,2,3-Benzenetricarboxylic acid (CAS 569-51-7)

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Alternate Names:
Hemimellitic acid
CAS Number:
569-51-7
Molecular Weight:
210.14
Molecular Formula:
C9H6O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2,3-Benzenetricarboxylic acid (BTCA) is an important component in many chemical reactions and has a wide range of applications in the fields of chemistry and biochemistry. It acts as a proton donor which allows it to serve as a catalyst in a variety of chemical reactions, such as the synthesis of polymers, dyes, and pigments. In addition, it can form complexes with metal ions, which can be used to extract metals from solution. Therefore, 1,2,3-Benzenetricarboxylic acid is used as a chelating agent and as a buffer in biochemical assays. Moreover, it is known to inhibit the activity of certain enzymes, such as the enzyme cyclooxygenase-2 (COX-2), which is involved in the synthesis of prostaglandins. Furthermore, it inhibits the growth of certain types of cancer cells and reduces inflammation.


1,2,3-Benzenetricarboxylic acid (CAS 569-51-7) References

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  2. Temporal trends in motor vehicle and secondary organic tracers using in situ methylation thermal desorption GCMS.  |  Sheesley, RJ., et al. 2010. Environ Sci Technol. 44: 9398-404. PMID: 21105701
  3. Syntheses, structures and properties of two unusual silver-organic coordination networks: 1D→1D tubular intertwinement and existence of an infinite winding water chain.  |  Li, B., et al. 2011. Dalton Trans. 40: 788-92. PMID: 21152508
  4. Assembly of 1,2,3-benzenetricarboxylic acid and sliver(I) metal center to a novel 3D supramolecular framework: syntheses, structure and properties.  |  Liu, JY., et al. 2012. Spectrochim Acta A Mol Biomol Spectrosc. 89: 7-10. PMID: 22245883
  5. Tricarboxylate carrier of bovine liver mitochondria. Purification and reconstitution.  |  Claeys, D. and Azzi, A. 1989. J Biol Chem. 264: 14627-30. PMID: 2549027
  6. Single-Molecule-Based Electroluminescent Device as Future White Light Source.  |  Usman, M., et al. 2019. ACS Appl Mater Interfaces. 11: 4084-4092. PMID: 30604616
  7. Evidence for the occurrence of the malate-citrate shuttle in intact Ehrlich ascites tumor cells.  |  Eboli, ML. and Galeotti, T. 1981. Biochim Biophys Acta. 638: 75-9. PMID: 7295712
  8. Cooperation between enzyme and transporter in the inner mitochondrial membrane of yeast. Requirement for mitochondrial citrate synthase for citrate and malate transport in Saccharomyces cerevisiae.  |  Sandor, A., et al. 1994. J Biol Chem. 269: 29609-12. PMID: 7961948
  9. The mitochondrial tricarboxylate carrier.  |  Azzi, A., et al. 1993. J Bioenerg Biomembr. 25: 515-24. PMID: 8132491

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2,3-Benzenetricarboxylic acid, 5 g

sc-255905
5 g
$69.00