Molecular structure of 1,2,3,7,8-Pentachlorodibenzo-p-dioxin, CAS Number: 40321-76-4
1,2,3,7,8-Pentachlorodibenzo-p-dioxin (CAS 40321-76-4)
Alternate Names:
1,2,3,7,8-PeCDD; D 54
Application:
1,2,3,7,8-Pentachlorodibenzo-p-dioxin is a toxic polychlorinated dibenzo-p-dioxin
CAS Number:
40321-76-4
Molecular Weight:
356.42
Molecular Formula:
C12H3Cl5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1,2,3,7,8-Pentachlorodibenzo-P-dioxin, a member of the dioxin family, is a highly toxic and persistent organic pollutant (POP) with detrimental effects on the environment. It is generated as a byproduct during industrial processes such as incineration, paper bleaching, and pesticide manufacturing. 1,2,3,7,8-Pentachlorodibenzo-P-dioxin possesses high lipophilicity, enabling its solubility in fats and subsequent accumulation in fatty tissue. It can interfere with DNA functioning, disrupting the normal cellular processes.
1,2,3,7,8-Pentachlorodibenzo-p-dioxin (CAS 40321-76-4) References
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- Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDS/PCDFS and PCBS. | Smialowicz, RJ., et al. 2008. Toxicol Appl Pharmacol. 227: 477-84. PMID: 18190939
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- Determination of some congeners of polychlorinated dibenzo-p-dioxins (PCDDs) in milk using gas chromatography. | Khan, IA. and Maqsood, ZT. 2009. Bull Environ Contam Toxicol. 82: 722-6. PMID: 19280092
- Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on I-compounds in hepatic DNA of Sprague-Dawley rats: sex-specific effects and structure-activity relationships. | Randerath, K., et al. 1990. Toxicol Appl Pharmacol. 103: 271-80. PMID: 2158676
- Reductive dechlorination of 1,2,3,7,8-pentachlorodibenzo-p-dioxin and Aroclor 1260, 1254 and 1242 by a mixed culture containing Dehalococcoides mccartyi strain 195. | Zhen, H., et al. 2014. Water Res. 52: 51-62. PMID: 24462927
- Organ-specific effects of long term feeding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,7,8-pentachlorodibenzo-p-dioxin on I-compounds in hepatic and renal DNA of female Sprague-Dawley rats. | Randerath, K., et al. 1988. Carcinogenesis. 9: 2285-9. PMID: 3191574
- Computational study on the metabolic activation mechanism of PeCDD by Cytochrome P450 1A1. | Zhu, L., et al. 2021. J Hazard Mater. 405: 124276. PMID: 33158646
- Trends in concentrations of selected dioxins and furans across various stages of kidney function for US adults. | Jain, RB. 2021. Environ Sci Pollut Res Int. 28: 43763-43776. PMID: 33840024
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,2,3,7,8-Pentachlorodibenzo-p-dioxin, 2.5 mg | sc-460182 | 2.5 mg | $367.00 |