![1,1′-Ethylidenebis[L-tryptophan] (CAS 132685-02-0) - chemical structure image](https://media.scbt.com/product/1-1prime-ethylidenebis-l-tryptophan-132685-02-0-structure_36_81_b_368143.jpg)
![1,1′-Ethylidenebis[L-tryptophan] (CAS 132685-02-0) - chemical structure image](https://media.scbt.com/product/1-1prime-ethylidenebis-l-tryptophan-132685-02-0-structure_36_81_t_368143.jpg "Molecular structure of 1,1′-Ethylidenebis[L-tryptophan], CAS Number: 132685-02-0")
Molecular structure of 1,1′-Ethylidenebis[L-tryptophan], CAS Number: 132685-02-0
1,1′-Ethylidenebis[L-tryptophan] (CAS 132685-02-0)
Alternate Names:
USP Tryptophan Related Compound A; 1,1′-Ethylidenebis-L-tryptophan
CAS Number:
132685-02-0
Purity:
≥96%
Molecular Weight:
434.49
Molecular Formula:
C24H26N4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
1,1′-Ethylidenebis[L-tryptophan] (EBT) has held a significant role as a organic compound in both scientific research and industrial applications. 1,1′-Ethylidenebis[L-tryptophan], an aromatic compound, stands as a composite of two tryptophan molecules united by a carbon-carbon double bond. It serves as a valuable precursor for synthesizing a wide array of compounds, including amino acids and peptides. Its utilization extends to the field of biochemistry, where it aids in unraveling the structure and functionality of proteins and enzymes. While the exact mechanism of action of 1,1′-Ethylidenebis[L-tryptophan] remains partially elusive, it is believed to engage in hydrogen bonding and hydrophobic interactions when interacting with proteins and enzymes. These interactions potentially lead to the formation of complexes, thereby facilitating the exploration of their structure and function.
1,1′-Ethylidenebis[L-tryptophan] (CAS 132685-02-0) References
- L-tryptophan contaminant 'peak E' induces the release of IL-5 and IL-10 by peripheral blood mononuclear cells from patients with functional somatic syndromes. | Barth, H., et al. 2001. Clin Exp Immunol. 126: 187-92. PMID: 11703359
- Identification of decomposition products of 1,1'-ethylidenebis [L-tryptophan], a compound associated with eosinophilia-myalgia syndrome. | Driskell, WJ., et al. 1992. Bull Environ Contam Toxicol. 48: 679-87. PMID: 1504513
- Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder. | Garbarino, VR., et al. 2019. Pharmacol Res. 140: 85-99. PMID: 30009933
- Chemical Characterization and DNA Fingerprinting of Griffonia simplicifolia Baill. | Vigliante, I., et al. 2019. Molecules. 24: PMID: 30875930
- 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. | Maffei, ME. 2020. Int J Mol Sci. 22: PMID: 33375373
- Detection of impurities in dietary supplements containing L-tryptophan. | Karakawa, S., et al. 2022. Amino Acids. 54: 835-839. PMID: 35043227
- Regulatory science of natural products. | Goda, Y. 2022. J Nat Med. 76: 732-747. PMID: 35870047
- Analytical Chemistry of Impurities in Amino Acids Used as Nutrients: Recommendations for Regulatory Risk Management. | Karakawa, S., et al. 2022. Nutrients. 14: PMID: 35889795
- Sensitive determination of 1,1'-ethylidenebis(L-tryptophan) in L-tryptophan by gradient HPLC with fluorimetric detection. | Knight, BI. and Davidson, AG. 1993. J Pharm Biomed Anal. 11: 85-8. PMID: 8466962
- 1,1'-Ethylidenebis[L-tryptophan], a contaminant implicated in L-tryptophan eosinophilia myalgia syndrome, suppresses mRNA expression of hypothalamic corticotropin-releasing hormone in Lewis (LEW/N) rat brain. | Brady, LS., et al. 1994. Neuroimmunomodulation. 1: 59-65. PMID: 8528886
- 1,1'-Ethylidenebis[L-tryptophan], an impurity in L-tryptophan associated with eosinophilia-myalgia syndrome, stimulates type I collagen gene expression in human fibroblasts in vitro. | Zangrilli, JG., et al. 1995. Biochem Mol Biol Int. 37: 925-33. PMID: 8624499
- Dot-like focal contacts in adherent eosinophils, their redistribution into peripheral belts, and correlated effects on cell migration and protected zone formation. | Tourkin, A., et al. 1996. J Cell Sci. 109 (Pt 8): 2169-77. PMID: 8856513
- EBT, a tryptophan contaminant associated with eosinophilia myalgia syndrome, is incorporated into proteins during translation as an amino acid analog. | Buss, WC., et al. 1996. Autoimmunity. 25: 33-45. PMID: 9161698
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,1′-Ethylidenebis[L-tryptophan], 10 mg | sc-497957B | 10 mg | $255.00 | |||
1,1′-Ethylidenebis[L-tryptophan], 25 mg | sc-497957C | 25 mg | $408.00 | |||
1,1′-Ethylidenebis[L-tryptophan], 50 mg | sc-497957 | 50 mg | $561.00 | |||
1,1′-Ethylidenebis[L-tryptophan], 100 mg | sc-497957D | 100 mg | $1020.00 | |||
1,1′-Ethylidenebis[L-tryptophan], 250 mg | sc-497957A | 250 mg | $1836.00 | |||
1,1′-Ethylidenebis[L-tryptophan], 1 g | sc-497957E | 1 g | $2448.00 |