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1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate (CAS 41085-99-8)

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Alternate Names:
DiI perchlorate; 3H-Indolium; 2-(3-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol- 2-ylidene)-1-propenyl)-3,3-dimethyl-1-octadecyl-, perchlorate
Application:
CAS Number:
41085-99-8
Molecular Weight:
933.87
Molecular Formula:
C59H97ClN2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is a lipophilic dye used to record membrane voltage for fluidity studies. This retrograde stain is useful in staining neurons in vitro and in vivo because the stain is relatively nontoxic to cell bodies and the dye is retained in neurons. In addition, 1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is an ideal retrograde and anterograde tracer to label the processes as well as the cell bodies of cultured neurons.


1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate (CAS 41085-99-8) References

  1. Projections from the hypothalamus to the posterior lobe in rats during ontogenesis: 1,1'-dioctadecyl-3,3,3', 3'-tetramethylindocarbocyanine perchlorate tracing study.  |  Makarenko, IG., et al. 2000. J Comp Neurol. 422: 327-37. PMID: 10861510
  2. Lateral diffusion of 1,1'-dioctadecyl-3,3,3'3'-tetramethylindocarbocyanine perchlorate at the interfaces of C18 and chromatographic solvents.  |  Swinton, DJ. and Wirth, MJ. 2000. Anal Chem. 72: 3725-30. PMID: 10959955
  3. [Involvement of accessory neurosecretory nuclei of hypothalamus in the formation of hypothalamohypophyseal system during prenatal and postnatal development in rats].  |  Makarenko, IG., et al. 2002. Ontogenez. 33: 43-9. PMID: 11862695
  4. Early ingrowth of thalamocortical afferents to the neocortex of the prenatal rat.  |  Catalano, SM., et al. 1991. Proc Natl Acad Sci U S A. 88: 2999-3003. PMID: 2014221
  5. Retinal axon pathfinding in the optic chiasm: divergence of crossed and uncrossed fibers.  |  Godement, P., et al. 1990. Neuron. 5: 173-86. PMID: 2383400
  6. Organization of corticocortical connections in human visual cortex.  |  Burkhalter, A. and Bernardo, KL. 1989. Proc Natl Acad Sci U S A. 86: 1071-5. PMID: 2464827
  7. Dil and diO: versatile fluorescent dyes for neuronal labelling and pathway tracing.  |  Honig, MG. and Hume, RI. 1989. Trends Neurosci. 12: 333-5, 340-1. PMID: 2480673
  8. [The integrity study on PEG-PCL micelles transcellular transported across MDCK epithelial cell monolayer using FRET technology].  |  Li, R., et al. 2016. Yao Xue Xue Bao. 51: 1316-24. PMID: 29906041
  9. High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model.  |  Ribieras, AJ., et al. 2022. J Vis Exp.. PMID: 35377355
  10. Development of visualization and analysis methods for evaluating intratumoral nanoparticle kinetics for tumor-targeted drug delivery using Förster resonance energy transfer in vivo live imaging and tissue clearing techniques.  |  Togami, K., et al. 2023. J Pharm Biomed Anal. 223: 115127. PMID: 36327577
  11. Presentation of human neocortical neurons stained with the carbocyanine dye dil compared to the Golgi silver impregnation technique.  |  Supprian, T., et al. 1993. J Hirnforsch. 34: 403-6. PMID: 7505791
  12. Direct patch recording from identified presynaptic terminals mediating glutamatergic EPSCs in the rat CNS, in vitro.  |  Forsythe, ID. 1994. J Physiol. 479 (Pt 3): 381-7. PMID: 7837096
  13. Neural projections of the pineal organ in the larval sea lamprey (Petromyzon marinus L.) revealed by indocarbocyanine dye tracing.  |  Yáñez, J., et al. 1993. Neurosci Lett. 164: 213-6. PMID: 8152603
  14. Sensory innervation of the guinea pig extraocular muscles: a 1,1'-dioctadecyl-3,3,3'3'-tetramethylindocarbocyanine perchlorate tracing and calcitonin gene-related peptide immunohistochemical study.  |  Aigner, M., et al. 1997. J Comp Neurol. 380: 16-22. PMID: 9073080

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate, 100 mg

sc-213424
100 mg
$170.00