1,1prime-Dioctadecyl-3,3,3prime,3prime-tetramethylindocarbocyanine perchlorate CAS: 41085-99-8
MF: C59H97ClN2O4
MW: 933.87
A dye used to record membrane voltage.

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate (CAS 41085-99-8)

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate | CAS 41085-99-8 is rated 5.0 out of 5 by 1.
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Alternate Names: DiI perchlorate; 3H-Indolium; 2-(3-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol- 2-ylidene)-1-propenyl)-3,3-dimethyl-1-octadecyl-, perchlorate
Application: 1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is a dye used to record membrane voltage
CAS Number: 41085-99-8
Molecular Weight: 933.87
Molecular Formula: C59H97ClN2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate is a lipophilic dye used to record membrane voltage for fluidity studies. This retrograde stain is useful in staining neurons in vitro and in vivo because the stain is relatively nontoxic to cell bodies and the dye is retained in neurons. In addition, 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate is an ideal retrograde and anterograde tracer to label the processes as well as the cell bodies of cultured neurons.


References

1. Honig, M.G. and Hume, R.I. 1989. Trends Neurosci. 12: 333-5, 340. PMID: 2480673
2. Godement, P., et al. 1990. Neuron. 5: 173-186. PMID: 2383400

Appearance :
Powder or crystalline powder
Physical State :
Solid
Storage :
Store at 4° C
Melting Point :
68° C (dec.)
Fluoresence :
λex 550 nm, λem 565 nm in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16212735
MDL Number :
MFCD00142354
SMILES :
CCCCCCCCCCCCCCCCCCN\\1C2=CC=CC=C2C(/C1=C/C=C\\C3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCCCCCCCC)(C)C.[O-]Cl(=O)(=O)=O

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Certificate of Analysis

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1,1prime-Dioctadecyl-3,3,3prime,3prime-tetramethylindocarbocyanine perchlorate (CAS 41085-99-8) Product Citations

See how others have used 1,1prime-Dioctadecyl-3,3,3prime,3prime-tetramethylindocarbocyanine perchlorate (CAS 41085-99-8). Click on the entry to view the PubMed entry .

Citations 1 to 4 of 4 total

PMID: # 26201614  Xu, XX. et al. 2016. Eur J Pain. 20: 552-63.

PMID: # 26742944  Wang, JT. et al. 2016. J Control Release. 224: 22-32.

PMID: # 26184049  Stirland, DL. et al. 2015. Journal of controlled release : official journal of the Controlled Release Society. 214: 85-93.

PMID: # 25607843  Steculorum, SM. et al. 2015. The Journal of clinical investigation. 125: 846-58.

Citations 1 to 4 of 4 total
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Rated 5 out of 5 by from Solorio L; et al Solorio L; et al. (PubMed ID: 26175342) determined that 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate, reduced burst release in Phase-sensitive in situ forming implants. -SCBT Publication Review
Date published: 2015-03-28
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