Date published: 2025-10-17

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1,1′-Azobis(cyclohexanecarbonitrile) (CAS 2094-98-6)

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Alternate Names:
1,1′-Azobis(cyanocyclohexane); ACHN; VAZO™ catalyst 88 free radical source
Application:
CAS Number:
2094-98-6
Purity:
≥97%
Molecular Weight:
244.34
Molecular Formula:
C14H20N4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,1′-Azobis(cyclohexanecarbonitrile) is a more efficient radical initiator than AIBN has been employed to initiate primary radical reactions. 1,1′-Azobis(cyclohexanecarbonitrile) (ABCN) is a versatile organic compound utilized in the field of organic synthesis and material development. It presents as a white solid that dissolves readily in organic solvents like ethanol and acetone. 1,1′-Azobis(cyclohexanecarbonitrile) serves as a flexible reagent in a range of organic reactions, including the synthesis of aldehydes, ketones, and nitriles. Additionally, it acts as a catalyst and polymerization initiator for the production of polymers.


1,1′-Azobis(cyclohexanecarbonitrile) (CAS 2094-98-6) References

  1. Synthesis by radical cyclization and cytotoxicity of highly potent bioreductive alicyclic ring fused [1,2-a]benzimidazolequinones.  |  Lynch, M., et al. 2007. Chemistry. 13: 3218-26. PMID: 17200920
  2. Characterization of particle morphology of biochanin A molecularly imprinted polymers and their properties as a potential sorbent for solid-phase extraction.  |  Chrzanowska, AM., et al. 2015. Mater Sci Eng C Mater Biol Appl. 49: 793-798. PMID: 25687010
  3. Iron-Based ICAR ATRP of Styrene with ppm Amounts of FeIIIBr3 and 1,1'-Azobis(cyclohexanecarbonitrile).  |  Mukumoto, K., et al. 2012. ACS Macro Lett. 1: 599-602. PMID: 35607069
  4. Sustainable Protocol for the Synthesis of 2',3'-Dideoxynucleoside and 2',3'-Didehydro-2',3'-dideoxynucleoside Derivatives.  |  Martín-Nieves, V., et al. 2022. Molecules. 27: PMID: 35807233
  5. Carbocyclization by radical closure onto O-trityl oximes: Dramatic effect of diphenyl diselenide  |  Clive, D. L., Pham, M. P., & Subedi, R. 2007. Journal of the American Chemical Society. 129(9): 2713-2717.
  6. Polyacrylates containing dansyl semicarbazide units sensitive for some structures in solution and film  |  Buruiana, E. C., Chibac, A. L., & Buruiana, T. 2010. Photochemistry and Photobiology A: Chemistry. 213(2-3): 107-113.
  7. Synthesis and characterization of new optically active poly (acrylamide/methacrylurea-co-vinyl acetate) copolymers with dansyl units  |  Murariu, M., & Buruiana, E. C. 2015. Designed Monomers and Polymers. 18(2): 118-128.
  8. Synthesis and application of a molecularly imprinted polymer in the solid-phase extraction of ketoprofen from wastewater  |  Zunngu, S. S., Madikizela, L. M., Chimuka, L., & Mdluli, P. S. 2017. Comptes Rendus Chimie. 20(5): 585-591.
  9. Synthesis of copper (II) ion‐imprinted polymers via suspension polymerization  |  Chaipuang, A., Phungpanya, C., Thongpoon, C., Watla‐iad, K., Inkaew, P., Machan, T., & Suwantong, O. 2018. Polymers for Advanced Technologies. 29(12): 3134-3141.
  10. Solid thermal explosion of autocatalytic material based on nonisothermal experiments: Multistage evaluations for 2, 2′‐azobis (2‐methylpropionitrile) and 1, 1′‐azobis (cyclohexanecarbonitrile)  |  Yu, A. D., Cao, C. R., Pan, X. H., Shu, C. M., & Wang, W. J. 2019. Process Safety Progress. 38(4): e12058.
  11. Copper-Catalyzed Oxidative Cascade Cyclization of Activated Alkenes with Azobis Compounds: Access to Cyano-Substituted Benzimidazo [2, 1-a] isoquinolin-6 (5 H)-ones  |  Tang, Y., Huang, H., Li, M., Wang, F., Hu, X., & Zhang, X. 2021. Russian Journal of Organic Chemistry. 57(12): 2010-2017.
  12. Thermal stability and decomposition mechanism analysis of 1, 1'-Azobis (cyclohexanecarbonitrile) by STA, DSC, ARC and TG-FTIR  |  Li, F. H., Liu, S. H., Guo, R. L., & Hou, H. Y. 2023. Journal of Loss Prevention in the Process Industries. 83: 105044.
  13. Implementation of thermo-responsive polymer coatings for an early warning against critical temperature states of thermo-sensitive electronic devices with metal oxide (MOx) gas sensors  |  Bautista-Anguís, D., Wolfberger, A., Rabe, M., Tomaszczyk, S., & Schlögl, S. 2023. Progress in Organic Coatings. 178: 107444.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,1′-Azobis(cyclohexanecarbonitrile), 25 g

sc-237651
25 g
$61.00