1,1-Dimethyl-4-phenylpiperazinium iodide (CAS 54-77-3)

1,1-Dimethyl-4-phenylpiperazinium iodide is a compound that functions as a nicotinic acetylcholine receptor agonist. It acts by binding to the nicotinic acetylcholine receptors, the α4β2 subtype, leading to the activation of these receptors. This activation results in the opening of ion channels, allowing the influx of cations such as sodium and calcium into the cell. The influx of these cations depolarizes the cell membrane, leading to the generation of action potentials. Mode of action involves enhancing cholinergic neurotransmission, which can have implications in various experimental related to the study of neuronal signaling, synaptic transmission, and ion channel function. Its interaction with nicotinic acetylcholine receptors can be utilized in settings to investigate the role of these receptors in various physiological and pathological processes. 1,1-Dimethyl-4-phenylpiperazinium iodide′s functional role lies in its ability to modulate nicotinic acetylcholine receptor activity, making it useful for studying cholinergic neurotransmission and related cellular processes.