Molecular structure of 1,1-Bis(methylthio)-2-nitroethylene, CAS Number: 13623-94-4
1,1-Bis(methylthio)-2-nitroethylene (CAS 13623-94-4)
Alternate Names:
Nitroketene dimethyl mercaptal
CAS Number:
13623-94-4
Molecular Weight:
165.23
Molecular Formula:
C4H7NO2S2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
1,1-Bis(methylthio)-2-nitroethylene is a compound of notable interest in the field of organic chemistry, primarily due to its unique functional groups and their reactivity. The presence of both methylthio groups and a nitro group attached to an ethylene backbone offers a distinctive electronic configuration, which is pivotal in its reactivity and mechanism of action. This compound serves as a critical intermediate in the synthesis of various organic molecules, particularly in the development of novel compounds with potential applications in materials science and as reagents in chemical research. Its mechanism involves participating in reactions that leverage the electron-withdrawing nature of the nitro group, alongside the electron-donating methylthio groups, to facilitate nucleophilic substitutions, additions, or even rearrangement reactions under specific conditions.
1,1-Bis(methylthio)-2-nitroethylene (CAS 13623-94-4) References
- Affinity to the nicotinic acetylcholine receptor and insecticidal activity of chiral imidacloprid derivatives with a methylated imidazolidine ring. | Nishiwaki, H., et al. 2011. Biosci Biotechnol Biochem. 75: 780-2. PMID: 21512232
- Functional interaction of nicotinic acetylcholine receptors and Na+/K+ ATPase from Locusta migratoria manilensis (Meyen). | Bao, H., et al. 2015. Sci Rep. 5: 8849. PMID: 25743085
- Imidacloprid and Related Compounds: Structure and Water Solubility of N-Alkyl Derivatives of Imidacloprid. | Kagabu, S., et al. 1998. Biosci Biotechnol Biochem. 62: 1216-24. PMID: 27388647
- Synthesis and biological evaluation of ranitidine analogs as multiple-target-directed cognitive enhancers for the treatment of Alzheimer's disease. | Gao, J., et al. 2016. Bioorg Med Chem Lett. 26: 5573-5579. PMID: 27769620
- Electrophilically Activated Nitroalkanes in Reactions With Carbon Based Nucleophiles. | Aksenov, NA., et al. 2020. Front Chem. 8: 77. PMID: 32117896
- Synthesis of new functionalized thiazolo pyridine-fused and thiazolo pyridopyrimidine-fused spirooxindoles via one-pot reactions. | Nasri, S., et al. 2020. Heliyon. 6: e03687. PMID: 32258502
- [3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor. | Aksenov, AV., et al. 2021. Org Biomol Chem. 19: 7234-7245. PMID: 34387294
- Synthesis of spiroimidazopyridineoxindole, spiropyridopyrimidineoxindole and spiropyridodiazepineoxindole derivatives based on heterocyclic ketene aminals via a four-component reaction. | Rahimi, F., et al. 2019. RSC Adv. 9: 16384-16389. PMID: 35516376
- An efficient synthesis of new imidazo[1,2-a]pyridine-6-carbohydrazide and pyrido[1,2-a]pyrimidine-7-carbohydrazide derivatives via a five-component cascade reaction. | Hosseini, H. and Bayat, M. 2019. RSC Adv. 9: 7218-7227. PMID: 35519992
- Synthesis of highly functionalized thiazolo[3,2-a]pyridine derivatives via a five-component cascade reaction based on nitroketene N,S-acetal. | Razavi, ZS., et al. 2020. RSC Adv. 10: 31039-31048. PMID: 35520681
- Synthesis of 5-amino-N'-(9H-fluoren-9-ylidene)-8-nitro-7-aryl-1,2,3,7-tetrahydroimidazo[1,2-a]pyridine-6-carbohydrazide derivatives based on heterocyclic ketene aminals. | Hosseini, H. and Bayat, M. 2018. RSC Adv. 8: 41218-41225. PMID: 35559289
- Synthesis of diverse spiro-imidazo pyridine-indene derivatives via acid-promoted annulation reaction of bindone and heterocyclic ketene aminals. | Nasri, S., et al. 2022. Sci Rep. 12: 12550. PMID: 35869174
- Nitroenediamines (EDAMs), and N-methyl-1-(methylthio)-2-nitroethenamine (NMSM) derivatives: scaffolds for heterocycle molecular diversity (update from 2012 to 2021). | Abedinifar, F., et al. 2022. RSC Adv. 12: 30436-30456. PMID: 36337974
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,1-Bis(methylthio)-2-nitroethylene, 25 g | sc-237632 | 25 g | $93.00 |