Date published: 2025-10-2

1-800-457-3801

SCBT Portrait Logo
Seach Input

1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene (CAS 6683-46-1)

0.0(0)
Write a reviewAsk a question

Alternate Names:
1,2,3,4-Tetrahydro-1,1,4,4-tetramethylnaphthalene
Application:
1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene is a useful precursor to various other compounds, specifically MM 11253 (sc-361255)
CAS Number:
6683-46-1
Molecular Weight:
188.31
Molecular Formula:
C14H20
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene is a clear, scentless organic substance often utilized in fragrances, as a resin and coatings solvent, and as a foundational material in crafting other organic entities. This viscous liquid mixes well with nonpolar solutions like hexane and ether but doesn′t dissolve in water. Its versatile nature makes it pivotal in producing intricate organic structures, including steroids and alkaloids. Additionally, its role extends to being a solvent in creating resins, coatings, and glues. The compound′s distinct molecular configuration also serves as an insightful probe for examining organic reactions and their underlying processes.


1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene (CAS 6683-46-1) References

  1. Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.  |  Christie, VB., et al. 2008. Org Biomol Chem. 6: 3497-507. PMID: 19082150
  2. Synthetic retinoids: structure-activity relationships.  |  Barnard, JH., et al. 2009. Chemistry. 15: 11430-42. PMID: 19821467
  3. Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives.  |  Gurkan-Alp, AS., et al. 2012. Eur J Med Chem. 58: 346-54. PMID: 23142674
  4. Design and biological evaluation of synthetic retinoids: probing length vs. stability vs. activity.  |  Clemens, G., et al. 2013. Mol Biosyst. 9: 3124-34. PMID: 24108350
  5. Dye decolorization and detoxification potential of Ca-alginate beads immobilized manganese peroxidase.  |  Bilal, M. and Asgher, M. 2015. BMC Biotechnol. 15: 111. PMID: 26654190
  6. Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase.  |  Diaz, P., et al. 2016. J Med Chem. 59: 2579-95. PMID: 26918322
  7. Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids.  |  Haffez, H., et al. 2018. Bioorg Med Chem. 26: 1560-1572. PMID: 29439915
  8. Radical trans-Hydroboration of Alkynes with N-Heterocyclic Carbene Boranes.  |  Shimoi, M., et al. 2018. Angew Chem Int Ed Engl. 57: 9485-9490. PMID: 29845716
  9. Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways.  |  Chisholm, DR., et al. 2019. ACS Chem Biol. 14: 369-377. PMID: 30707838
  10. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB).  |  Jurutka, PW., et al. 2021. Int J Mol Sci. 22: PMID: 34830251

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene, 1 g

sc-258895
1 g
$42.00