Molecular structure of 1,1,1-Trifluoro-2-iodoethane, CAS Number: 353-83-3
1,1,1-Trifluoro-2-iodoethane (CAS 353-83-3)
Alternate Names:
2,2,2-Trifluoroethyl iodide, 2-Iodo-1,1,1-trifluoroethane
CAS Number:
353-83-3
Molecular Weight:
209.94
Molecular Formula:
C2H2F3I
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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1,1,1-Trifluoro-2-iodoethane is a versatile synthetic compound with applications in scientific and industrial domains. It finds use in the synthesis of specific organic molecules, including dyes, pigments, and polymers. Additionally, it has been valuable in researching biochemical processes, such as enzyme kinetics, and studying the structure and function of particular proteins.
1,1,1-Trifluoro-2-iodoethane (CAS 353-83-3) References
- Quantitative determination of vapor-phase compound A in sevoflurane anesthesia using gas chromatography-mass spectrometry. | Bouche, MP., et al. 2001. Clin Chem. 47: 281-91. PMID: 11159777
- Asymmetric synthesis of sterically and electronically demanding linear ω-trifluoromethyl containing amino acids via alkylation of chiral equivalents of nucleophilic glycine and alanine. | Wang, J., et al. 2011. J Org Chem. 76: 684-7. PMID: 21182272
- The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters. | Liang, A., et al. 2012. Chem Commun (Camb). 48: 8273-5. PMID: 22785428
- Palladium-catalyzed trifluoroethylation of terminal alkynes with 1,1,1-trifluoro-2-iodoethane. | Feng, YS., et al. 2013. Org Lett. 15: 936-9. PMID: 23373673
- Copper-promoted reductive coupling of aryl iodides with 1,1,1-trifluoro-2-iodoethane. | Xu, S., et al. 2014. Org Lett. 16: 2306-9. PMID: 24783963
- 2,2,2-Trifluoroethylation of Styrenes with Concomitant Introduction of a Hydroxyl Group from Molecular Oxygen by Photoredox Catalysis Activated by Visible Light. | Li, L., et al. 2015. Org Lett. 17: 4714-7. PMID: 26361093
- Regioselective 2,2,2-Trifluoroethylation of Imidazopyridines by Visible Light Photoredox Catalysis. | Zhu, M., et al. 2016. J Org Chem. 81: 7282-7. PMID: 27328667
- Copper-Catalyzed 2,2,2-Trifluoroethylthiolation of Aryl Halides. | Chen, S., et al. 2016. J Org Chem. 81: 7993-8000. PMID: 27477255
- Copper-catalyzed synthesis of 2,2,2-trifluoroethyl selenoethers and their insecticidal activities. | Dong, J., et al. 2018. Org Biomol Chem. 16: 9269-9273. PMID: 30465589
- Visible-Light-Induced Direct Csp2-H Radical Trifluoroethylation of Coumarins with 1,1,1-Trifluoro-2-iodoethane (CF3CH2I). | Chen, X., et al. 2021. J Org Chem. 86: 2772-2783. PMID: 33492969
- Effect of fluorine substitution on the OH-radical-induced electron-transfer reaction in aqueous solutions of fluorinated alkyl iodides | Mohan, H., Maity, D. K., & Mittal, J. P. 1994. Chemical physics letters. 220(6): 455-460.
- Effective α-Tosyloxylation of Ketones Using 1, 1, 1-Trifluoro-2-iodoethane as Catalyst | Zhang, B., Han, L., Hu, J., & Yan, J. 2014. Synthetic Communications. 44(22): 3264-3270.
- Nickel‐Catalyzed Direct Trifluoroethylation of Aryl Iodides with 1, 1, 1‐Trifluoro‐2‐Iodoethane via Reductive Coupling | Li, H., Sheng, J., Liao, G. X., Wu, B. B., Ni, H. Q., Li, Y., & Wang, X. S. 2020. Advanced Synthesis & Catalysis. 362(23): 5363-5367.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,1,1-Trifluoro-2-iodoethane, 5 g | sc-224846 | 5 g | $22.00 |