1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (CAS 6001-64-5)

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate is a chemical compound characterized by its structure which includes three chlorine atoms and a methyl group attached to a propanol backbone, along with half a molecule of water per molecule of the compound (hemihydrate). This compound is primarily known for its role as an intermediate in the synthesis of other chemical entities, particularly in the production of pharmaceuticals and pesticides. Its chemical reactivity stems from the presence of the trichloro-methyl group which makes it a valuable precursor in various organic synthesis reactions. In research, this compound has been utilized to study the mechanisms of halogenated alcohols in organic synthesis, exploring how the introduction of chlorine atoms affects reactivity and stability of the molecule. Researchers also investigate its potential to act as a building block in creating more complex molecules through reactions such as esterification or as a reactant in substitution reactions where the chlorine atoms are replaced under certain conditions. Moreover, its behavior as a hemihydrate is of interest in studies involving crystallography and solid-state chemistry, where the interaction of water molecules with organic compounds can significantly influence their physical properties and stability. Through these applications, 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate serves as a versatile tool in advancing our understanding of chemical synthesis processes and material science.