Date published: 2025-9-17

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1,1,1,3,3,3-Hexafluoro-2-propanol-d2 (CAS 38701-74-5)

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Alternate Names:
Deuterated 1,1,1,3,3,3-hexafluoro-2-propanol; Deuterated HFP; HFP-d2; Hexafluoroisopropanol-d2
Application:
1,1,1,3,3,3-Hexafluoro-2-propanol-d2 is a stable isotope used for biochemical research
CAS Number:
38701-74-5
Molecular Weight:
170.05
Molecular Formula:
C3D2F6O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,1,1,3,3,3-Hexafluoro-2-propanol-d2 is widely utilized in research focusing on nuclear magnetic resonance (NMR) spectroscopy due to its properties as a deuterated solvent. This compound provides an inert environment that minimizes background interference, facilitating the accurate analysis of reactive or unstable substances in NMR studies. Researchers employ 1,1,1,3,3,3-Hexafluoro-2-propanol-d2 to enhance the resolution and clarity of spectroscopic measurements, particularly when observing proton environments. Additionally, this solvent is used in the study of hydrogen bonding and molecular interactions due to its strong electronegative characteristics, which can influence the behavior of solutes at a molecular level.


1,1,1,3,3,3-Hexafluoro-2-propanol-d2 (CAS 38701-74-5) References

  1. Structure and solvation of melittin in 1,1,1,3,3,3-hexafluoro-2-propanol/water.  |  Gerig, JT. 2004. Biophys J. 86: 3166-75. PMID: 15111429
  2. Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering.  |  Zhang-Haagen, B., et al. 2016. PLoS One. 11: e0150267. PMID: 26919121
  3. Solvothermally Mediated Self-Assembly of Ultralong Peptide Nanobelts Capable of Optical Waveguiding.  |  Li, Y., et al. 2016. Small. 12: 2575-9. PMID: 27028848
  4. Actin-Induced Structure in the Beta-Thymosin Family of Intrinsically Disordered Proteins.  |  Xue, B. and Robinson, RC. 2016. Vitam Horm. 102: 55-71. PMID: 27450730
  5. Characterization of linear mimetic peptides of Interleukin-22 from dissection of protein interfaces.  |  La Manna, S., et al. 2017. Biochimie. 138: 106-115. PMID: 28479106
  6. C4-arylation and domino C4-arylation/3,2-carbonyl migration of indoles by tuning Pd catalytic modes: Pd(i)-Pd(ii) catalysis vs. Pd(ii) catalysis.  |  Cheng, Y., et al. 2021. Chem Sci. 12: 3216-3225. PMID: 34164090
  7. Isotope Effects on Chemical Shifts in the Study of Hydrogen Bonds in Small Molecules.  |  Hansen, PE. 2022. Molecules. 27: PMID: 35458603
  8. Approaching isotropic charge transport of n-type organic semiconductors with bulky substituents.  |  Yu, CP., et al. 2021. Commun Chem. 4: 155. PMID: 36697635
  9. Bacteria inhabiting spider webs enhance host silk extensibility.  |  Tsiareshyna, M., et al. 2024. Sci Rep. 14: 11011. PMID: 38744937

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,1,1,3,3,3-Hexafluoro-2-propanol-d2, 1 g

sc-224855
1 g
$102.00