Date published: 2025-12-1

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1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol (CAS 718-64-9)

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Application:
1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol is an effective solvent for Cu(0)-mediated single electron transfer-living radical polymerization of methyl methacrylate and polymerization of styrene
CAS Number:
718-64-9
Molecular Weight:
244.13
Molecular Formula:
C9H6F6O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol is a fluorinated organic compound characterized by its unique structural features, including a hexafluoroisopropanol group attached to a phenyl ring. This chemical structure imparts distinctive physical and chemical properties, such as high electronegativity and lipophobicity due to the presence of fluorine atoms, alongside the aromatic character contributed by the phenyl group. In research contexts, this compound is particularly valued for its role as a building block in the synthesis of more complex fluorinated compounds which are crucial in the development of materials with specific desired properties such as resistance to solvents, acids, and bases, and increased thermal stability. The hydroxyl group in 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol offers an active site for various chemical reactions, making it useful in esterification and etherification reactions, which are fundamental in creating specialized esters and ethers that exploit the unique properties of fluorine atoms. Additionally, its application extends to the field of polymer chemistry, where it is used to modify the surface properties of polymers, enhancing their hydrophobicity and chemical resistance. This makes the compound a valuable agent in coatings and protective films, particularly in scenarios requiring robust performance under harsh chemical conditions.


1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol (CAS 718-64-9) References

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  5. Molecular mapping of poly(methyl methacrylate) super-helix stereocomplexes.  |  Christofferson, AJ., et al. 2015. Chem Sci. 6: 1370-1378. PMID: 29560224
  6. Synthesis and Functionalization of Periodic Copolymers.  |  Kubatzki, F., et al. 2017. Polymers (Basel). 9: PMID: 30970845
  7. Photo-on-Demand Base-Catalyzed Phosgenation Reactions with Chloroform: Synthesis of Arylcarbonate and Halocarbonate Esters.  |  Hashimoto, Y., et al. 2021. J Org Chem. 86: 9811-9819. PMID: 34182754
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol, 10 g

sc-224853
10 g
$127.00