Date published: 2026-4-26

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(R)-(+)-Limonene (CAS 5989-27-5)

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Alternate Names:
(+)-p-Mentha-1,8-diene; (+)-Carvene; (R)-4-Isopropenyl-1-methyl-1-cyclohexene
CAS Number:
5989-27-5
Purity:
≥99%
Molecular Weight:
136.23
Molecular Formula:
C10H16
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(R)-(+)-Limonene, also known as D-Limonene, is a monoterpene found in citrus oils, Cannabis, and many other plants such as rosemary. It′s a significant component of the oil obtained from citrus peels. This compound is recognized for its various biological activities. For instance, it′s known to inhibit the growth of a wide range of bacteria, including S. aureus, B. cereus, E. faecalis, E. coli, P. aeruginosa, K. pneumoniae, M. catarrhalis, and C. neoformans. In laboratory studies, it has been observed to hinder tumor growth and decrease the number of metastases in certain organs. It has also been seen to reverse doxorubicin-induced declines in glutathione (GSH) levels in rat kidneys. (R)-(+)-Limonene is used in a variety of applications, including as a flavoring and fragrance agent. It′s highly associated with plant and insect interactions due to its ability to attract insects. It′s the primary constituent of the essential oil extracted from Anethum sowa Roxb. (Indian dill). It′s also a key ingredient in cosmetic products, making it a frequently employed compound in the industry. This optically active form of limonene is present in a clear colorless liquid with a pleasant lemon-like odor. It′s been found in human epidermis, skin tissues, and various biofluids such as feces, urine, and blood. The compound primarily resides in the cytoplasm and membrane within the cell. Furthermore, it′s known that (R)-(+)-Limonene can be converted into other compounds via biological processes.


(R)-(+)-Limonene (CAS 5989-27-5) References

  1. Effects of R-(+)- and S-(-)-limonene on the respiratory tract in mice.  |  Larsen, ST., et al. 2000. Hum Exp Toxicol. 19: 457-66. PMID: 11125716
  2. Patch testing with oxidized R-(+)-limonene and its hydroperoxide fraction.  |  Matura, M., et al. 2003. Contact Dermatitis. 49: 15-21. PMID: 14641115
  3. Optimization of R-(+)-alpha-terpineol production by the biotransformation of R-(+)-limonene.  |  Bicas, JL., et al. 2008. J Ind Microbiol Biotechnol. 35: 1061-70. PMID: 18560915
  4. Isolation and screening of microorganisms for R-(+)-limonene and (-)-beta-pinene biotransformation.  |  Rottava, I., et al. 2010. Appl Biochem Biotechnol. 162: 719-32. PMID: 19950000
  5. Optimization of α-Terpineol production by the biotransformation of R-(+)-limonene and (-)-β-pinene.  |  Rottava, I., et al. 2011. Appl Biochem Biotechnol. 164: 514-23. PMID: 21234702
  6. Intra-molecular enantiomerism in R-(+)-Limonene as evidenced by the differential bond polarizabilities.  |  Shen, H., et al. 2014. Spectrochim Acta A Mol Biomol Spectrosc. 128: 838-43. PMID: 24704601
  7. Novel R-(+)-limonene-based thiosemicarbazones and their antitumor activity against human tumor cell lines.  |  Vandresen, F., et al. 2014. Eur J Med Chem. 79: 110-6. PMID: 24727464
  8. Comparative study of the bioconversion process using R-(+)- and S-(-)-limonene as substrates for Fusarium oxysporum 152B.  |  Molina, G., et al. 2015. Food Chem. 174: 606-13. PMID: 25529726
  9. Physical stability of R-(+)-Limonene emulsions stabilized by Ulva fasciata algae polysaccharide.  |  Shao, P., et al. 2016. Int J Biol Macromol. 92: 926-934. PMID: 27498413
  10. Antibacterial activities of R-(+)-Limonene emulsion stabilized by Ulva fasciata polysaccharide for fruit preservation.  |  Shao, P., et al. 2018. Int J Biol Macromol. 111: 1273-1280. PMID: 29415414
  11. Review of toxicological assessment of d-limonene, a food and cosmetics additive.  |  Ravichandran, C., et al. 2018. Food Chem Toxicol. 120: 668-680. PMID: 30075315
  12. Optimization of limonene biotransformation for the production of bulk amounts of α-terpineol.  |  Molina, G., et al. 2019. Bioresour Technol. 294: 122180. PMID: 31606595
  13. The interaction of a thiosemicarbazone derived from R - (+) - limonene with lipid membranes.  |  Marquezin, CA., et al. 2021. Chem Phys Lipids. 234: 105018. PMID: 33232725

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(R)-(+)-Limonene, 5 ml

sc-506058
5 ml
$168.00