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β-Glycerophosphate disodium salt (CAS 819-83-0)

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Alternate Names:
β-Glycerophosphate disodium salt is known as BGP.
Application:
β-Glycerophosphate disodium salt is a phosphate donor and a serine-threonine phosphatase inhibitor
CAS Number:
819-83-0
Molecular Weight:
216.04
Molecular Formula:
C3H7O6P•2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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β-Glycerophosphate disodium salt is a phosphate group donor in matrix mineralization studies. β-Glycerophosphate disodium salt accelerates calcification in vascular smooth muscle cells. β-Glycerophosphate disodium salt can promote bone matrix mineralization when delivered to osteoblasts by providing a source of phosphate ions.


β-Glycerophosphate disodium salt (CAS 819-83-0) References

  1. Biomimetic apatite coatings on micro-arc oxidized titania.  |  Song, WH., et al. 2004. Biomaterials. 25: 3341-9. PMID: 15020106
  2. Development of bioactive and biodegradable chitosan-based injectable systems containing bioactive glass nanoparticles.  |  Couto, DS., et al. 2009. Acta Biomater. 5: 115-23. PMID: 18835230
  3. Injectable and biodegradable thermosensitive hydrogels loaded with PHBHHx nanoparticles for the sustained and controlled release of insulin.  |  Peng, Q., et al. 2013. Acta Biomater. 9: 5063-9. PMID: 23036950
  4. A novel injectable temperature-sensitive zinc doped chitosan/β-glycerophosphate hydrogel for bone tissue engineering.  |  Niranjan, R., et al. 2013. Int J Biol Macromol. 54: 24-9. PMID: 23201776
  5. Influence of unmodified and β-glycerophosphate cross-linked chitosan on anti-Candida activity of clotrimazole in semi-solid delivery systems.  |  Szymańska, E., et al. 2014. Int J Mol Sci. 15: 17765-77. PMID: 25272230
  6. Injectable Chitosan/β-Glycerophosphate System for Sustained Release: Gelation Study, Structural Investigation, and Erosion Tests.  |  Dalmoro, A., et al. 2017. Curr Drug Deliv. 14: 216-223. PMID: 27440070
  7. Piperine induces osteoblast differentiation through AMPK-dependent Runx2 expression.  |  Kim, DY., et al. 2018. Biochem Biophys Res Commun. 495: 1497-1502. PMID: 29203239
  8. In situ formation of injectable chitosan-gelatin hydrogels through double crosslinking for sustained intraocular drug delivery.  |  Song, Y., et al. 2018. Mater Sci Eng C Mater Biol Appl. 88: 1-12. PMID: 29636124
  9. Thermosensitive chitosan gels containing calcium glycerophosphate.  |  Skwarczynska, AL., et al. 2018. Spectrochim Acta A Mol Biomol Spectrosc. 201: 24-33. PMID: 29727793
  10. Chitosan/β-glycerophosphate-based microparticles manufactured by laminar jet break-up technology.  |  Benamer, W., et al. 2018. J Microencapsul. 35: 407-420. PMID: 30134755
  11. Small molecules modified biomimetic gelatin/hydroxyapatite nanofibers constructing an ideal osteogenic microenvironment with significantly enhanced cranial bone formation.  |  Li, D., et al. 2018. Int J Nanomedicine. 13: 7167-7181. PMID: 30464466
  12. Injectable Thermosensitive Chitosan Solution with β-Glycerophosphate as an Optimal Submucosal Fluid Cushion for Endoscopic Submucosal Dissection.  |  Jeong, S., et al. 2021. Polymers (Basel). 13: PMID: 34067377
  13. Osteogenic Differentiation from Mouse Embryonic Stem Cells.  |  Alvandi, Z. and Opas, M. 2022. Methods Mol Biol. 2520: 261-264. PMID: 34611818

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

β-Glycerophosphate disodium salt, 25 g

sc-220452
25 g
$62.00

β-Glycerophosphate disodium salt, 100 g

sc-220452A
100 g
$117.00

β-Glycerophosphate disodium salt, 500 g

sc-220452B
500 g
$433.00

β-Glycerophosphate disodium salt, 1 kg

sc-220452C
1 kg
$724.00

β-Glycerophosphate disodium salt, 3 kg

sc-220452D
3 kg
$2050.00

β-Glycerophosphate disodium salt, 6 kg

sc-220452E
6 kg
$3580.00

Is this suitable for cell culture? I wonder if it is the same quality of SIGMA G9422 Thank you

Asked by: Adrian Campelo
This product has not been specifically tested for cell culture use and is not cell culture grade, however, most products can still be used in cell culture applications by following basic cell culture protocols, e.g. using cell culture grade/sterilized solvents, aseptic technique, and sterilely filtering in a sterile hood.
Answered by: Technical Support
Date published: 2019-03-10

Is it suitable for cell culture? I mean hFOB 1.19 cell line in my example

Asked by: MartaM
This product has not been specifically tested for cell culture use and is not cell culture grade, however, most products can still be used in cell culture applications by following basic cell culture protocols, e.g. using cell culture grade/sterilized solvents, aseptic technique, and sterilely filtering in a sterile hood.
Answered by: Technical Support
Date published: 2018-11-14

Is sc-220452 β-Glycerophosphate disodium salt from a biological source?

Asked by: ChemSynth123
Thank you for your question. β-Glycerophosphate disodium salt (CAS 154804-51-0): sc-220452 is synthetic and not from a biological source.
Answered by: Chemical Support 7
Date published: 2017-03-10

what is the price of beta glycerophosphate?

Asked by: navjot kanwar
Thank you for your question. Please contact one of our authorized distributors in India to request a price quote for, β-Glycerophosphate disodium salt (CAS 154804-51-0): sc-220452. I will provide a link below to the contact information for our distributors. You can also find them by searching under Distributors, under Resources on the menu at the bottom of our web site. https://www3.scbt.com/scbt/resources/distributors
Answered by: Technical Support
Date published: 2016-09-21
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Rated 5 out of 5 by from Various publications citeVarious publications cite -Glycerophosphate disodium salt as a phosphate group donor in matrix mineralization studies. It accelerates calcification in vascular smooth muscle cells. -SCBT Publication Review
Date published: 2015-07-08
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β-Glycerophosphate disodium salt is rated 5.0 out of 5 by 1.
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