β-(4-Hydroxyphenyl)ethyl iodoacetamide (CAS 53527-07-4)
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Alternate Names:
β-(4-Hydroxyphenyl)ethyl iodoacetamide is also known as N-Iodoacetyltyramine.
Application:
β-(4-Hydroxyphenyl)ethyl iodoacetamide is used in the iodine-125 labelling of various molecules for chemical analysis.
CAS Number:
53527-07-4
Molecular Weight:
305.12
Molecular Formula:
C10H12NO2I
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
β-(4-Hydroxyphenyl)ethyl iodoacetamide is a building block used in the iodine-125 labelling of various molecules for chemical analysis. It is a derivative of iodoacetamide, which is used in biochemistry for protein labeling and modification. β-(4-Hydroxyphenyl)ethyl iodoacetamide is a reactive compound that can undergo Michael addition with thiol groups of cysteine residues in proteins. This reaction forms a covalent bond between the compound and the protein, allowing for the specific labeling or modification of the cysteine residues. This property makes it a useful tool in proteomics research for studying protein structure and function.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
β-(4-Hydroxyphenyl)ethyl iodoacetamide (CAS 53527-07-4) References
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- Cysteine Trisulfide Protects E. coli from Electrophile-Induced Death through the Generation of Cysteine Hydropersulfide. | Henderson, CF., et al. 2020. Chem Res Toxicol. 33: 678-686. PMID: 31977195
- The reactions of hydropersulfides (RSSH) with myoglobin. | Álvarez, L., et al. 2020. Arch Biochem Biophys. 687: 108391. PMID: 32360749
- High-Precision Sulfur Metabolomics Innovated by a New Specific Probe for Trapping Reactive Sulfur Species. | Kasamatsu, S., et al. 2021. Antioxid Redox Signal. 34: 1407-1419. PMID: 33198504
- The role of glutamate oxaloacetate transaminases in sulfite biosynthesis and H2S metabolism. | Mellis, AT., et al. 2021. Redox Biol. 38: 101800. PMID: 33271457
- Lipophilic compounds in garlic decrease the toxicity of methylmercury by forming sulfur adducts. | Abiko, Y., et al. 2021. Food Chem Toxicol. 150: 112061. PMID: 33587975
- Characterization of Endogenous and Extruded H2S and Small Oxoacids of Sulfur (SOS) in Cell Cultures. | Scrivner, O., et al. 2021. ACS Chem Biol. 16: 1413-1424. PMID: 34374506
- Chemical Biology of Reactive Sulfur Species: Hydrolysis-Driven Equilibrium of Polysulfides as a Determinant of Physiological Functions. | Sawa, T., et al. 2022. Antioxid Redox Signal. 36: 327-336. PMID: 34409860
- Mass spectrometry-based direct detection of multiple types of protein thiol modifications in pancreatic beta cells under endoplasmic reticulum stress. | Li, X., et al. 2021. Redox Biol. 46: 102111. PMID: 34425387
- Expanding the Reactive Sulfur Metabolome: Intracellular and Efflux Measurements of Small Oxoacids of Sulfur (SOS) and H2S in Human Primary Vascular Cell Culture. | Scrivner, O., et al. 2021. Molecules. 26: PMID: 34885743
- Concentrations of nucleophilic sulfur species in small Indian mongoose (Herpestes auropunctatus) in Okinawa, Japan. | Horai, S., et al. 2022. Chemosphere. 295: 133833. PMID: 35120952
- Gut microbiota reinforce host antioxidant capacity via the generation of reactive sulfur species. | Uchiyama, J., et al. 2022. Cell Rep. 38: 110479. PMID: 35263581
- Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers. | Schilling, D., et al. 2022. Angew Chem Int Ed Engl. 61: e202203684. PMID: 35506673
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-(4-Hydroxyphenyl)ethyl iodoacetamide, 100 mg | sc-473766 | 100 mg | $346.00 | |||
β-(4-Hydroxyphenyl)ethyl iodoacetamide, 250 mg | sc-473766A | 250 mg | $600.00 |