Date published: 2026-5-18

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(2S)-OMPT (CAS 1217471-69-6)

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Application:
(2S)-OMPT is a potent lipid mediator
CAS Number:
1217471-69-6
Purity:
>98%
Molecular Weight:
669.0
Molecular Formula:
C22H43O6PS•2(C2H5)3N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(2S)-OMPT is a molecule of interest in enzymology and metabolic pathway research. It is often used to probe the specificity and mechanism of action of methyltransferases, as it can serve as a substrate mimic or inhibitor. Studies involving (2S)-OMPT contribute to a deeper understanding of the methylation processes that occur in various biological systems. Researchers may also use (2S)-OMPT to investigate the regulation of epigenetic markers, which play a significant role in gene expression and can impact cellular function and differentiation. Additionally, in the field of chemical biology, (2S)-OMPT provides insights into the development of novel assays for detecting enzymatic activity related to methylation, which is important for advancing diagnostic tools and techniques.


(2S)-OMPT (CAS 1217471-69-6) References

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  2. Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid.  |  Santos, WL., et al. 2004. Bioorg Med Chem Lett. 14: 3473-6. PMID: 15177455
  3. IL-4 regulates MEK expression required for lysophosphatidic acid-mediated chemokine generation by human mast cells.  |  Lin, DA. and Boyce, JA. 2005. J Immunol. 175: 5430-8. PMID: 16210650
  4. Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?  |  Zhao, C., et al. 2008. Mol Pharmacol. 73: 587-600. PMID: 18006645
  5. The synergistic effects of lysophosphatidic acid receptor agonists and calcitriol on MG63 osteoblast maturation at titanium and hydroxyapatite surfaces.  |  Mansell, JP., et al. 2010. Biomaterials. 31: 199-206. PMID: 19796809
  6. Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid.  |  Motiejūnaitė, R., et al. 2014. Microvasc Res. 93: 62-71. PMID: 24681425
  7. Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis.  |  Lin, KH., et al. 2016. Sci Rep. 6: 27050. PMID: 27244685
  8. Lysophosphatidic acid regulates the motility of MCF10CA1a breast cancer cell sheets via two opposing signaling pathways.  |  Stuelten, CH., et al. 2018. Cell Signal. 45: 1-11. PMID: 29337044
  9. Lysophosphatidic acid enhanced the osteogenic and angiogenic capability of osteoblasts via LPA1/3 receptor.  |  Chen, X., et al. 2019. Connect Tissue Res. 60: 85-94. PMID: 29447019
  10. LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer.  |  Lin, YC., et al. 2018. Biochim Biophys Acta Mol Cell Biol Lipids. 1863: 1305-1315. PMID: 30053596
  11. Effects of lysophosphatidic acid (LPA) receptor-2 (LPA2) and LPA3 on the regulation of chemoresistance to anticancer drug in lung cancer cells.  |  Ueda, N., et al. 2020. Cell Signal. 69: 109551. PMID: 32006610
  12. Roles of endothelial cells in the regulation of cell motility via lysophosphatidic acid receptor-2 (LPA2) and LPA3 in osteosarcoma cells.  |  Minami, K., et al. 2021. Exp Mol Pathol. 118: 104596. PMID: 33347862
  13. Transcriptional regulation of lysophosphatidic acid receptors 2 and 3 regulates myeloid commitment of hematopoietic stem cells.  |  Lin, KH., et al. 2021. Am J Physiol Cell Physiol. 320: C509-C519. PMID: 33406026
  14. Paradoxical downregulation of LPAR3 exerts tumor-promoting activity through autophagy induction in Ras-transformed cells.  |  Hwang, SH., et al. 2022. BMC Cancer. 22: 969. PMID: 36088312
  15. TXA2 mediates LPA1-stimulated uterine contraction in late pregnant mouse.  |  Prakash, E., et al. 2023. Prostaglandins Other Lipid Mediat. 167: 106736. PMID: 37062326

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(2S)-OMPT, 500 µg

sc-223505
500 µg
$116.00

(2S)-OMPT, 1 mg

sc-223505A
1 mg
$221.00