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ZNF207 Antibody (A-7): sc-271277

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  • ZNF207 Antibody (A-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 1-184 mapping at the N-terminus of ZNF207 of human origin
  • recommended for detection of ZNF207 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNF207 Antibody (A-7) for WB and IHC(P) applications. These reagents are now offered in bundles with ZNF207 Antibody (A-7) (see ordering information below).
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    ZNF207 Antibody (A-7) is a mouse monoclonal IgG1 antibody that detects ZNF207 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ZNF207, a 478 amino acid protein, is primarily localized in the nucleus and is characterized by the presence of two C2H2-type zinc finger domains, which are crucial for its role as a transcription factor. ZNF207 (A-7) antibody recognizes a protein that binds DNA through these zinc fingers to regulate gene expression, making ZNF207 an important player in cellular processes such as development, differentiation, and response to environmental signals. Anti-ZNF207 antibody (A-7) targets a protein that is expressed ubiquitously across tissues, with three isoforms resulting from alternative splicing events. Understanding ZNF207′s role in transcriptional regulation is vital, as dysregulation of zinc-finger proteins has been implicated in various diseases, including cancer, highlighting the significance of ZNF207 monoclonal antibody (A-7) in research and diagnostic applications.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    ZNF207 Antibody (A-7) References:

    1. Oncogenic HER2 fusions in gastric cancer.  |  Yu, DH., et al. 2015. J Transl Med. 13: 116. PMID: 25889497
    2. A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells.  |  Fang, F., et al. 2018. Nat Commun. 9: 4384. PMID: 30349051
    3. [Expression of ZNF207 in hepatocellular carcinoma and its significance].  |  Zhou, C. and Li, N. 2019. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 44: 406-412. PMID: 31113916
    4. System analysis based on the cancer-immunity cycle identifies ZNF207 as a novel immunotherapy target for hepatocellular carcinoma.  |  Wang, X., et al. 2022. J Immunother Cancer. 10: PMID: 35246476
    5. Identification of Potential Diagnostic Genes of HIV-Infected Immunological Non-Responders on Bioinformatics Analysis.  |  Ding, Y., et al. 2023. J Inflamm Res. 16: 1555-1570. PMID: 37082297
    6. Transcriptomic correlates of cell cycle checkpoints with distinct prognosis, molecular characteristics, immunological regulation, and therapeutic response in colorectal adenocarcinoma.  |  Wang, H., et al. 2023. Front Immunol. 14: 1291859. PMID: 38143740
    7. Discovery of Novel N-(Anthracen-9-ylmethyl) Benzamide Derivatives as ZNF207 Inhibitors Promising in Treating Glioma.  |  Zhang, M., et al. 2024. J Med Chem. 67: 3909-3934. PMID: 38377560
    8. Zinc finger Protein207 orchestrates glioma migration through regulation of epithelial-mesenchymal transition.  |  Zhao, C., et al. 2024. Environ Toxicol.. PMID: 38591780
    9. Pan-cancer bioinformatics indicates zinc finger protein 207 is a promising prognostic biomarker and immunotherapeutic target.  |  Hu, Q., et al. 2024. J Leukoc Biol. 117: PMID: 38970506
    10. ZNF207, a ubiquitously expressed zinc finger gene on chromosome 6p21.3.  |  Pahl, PM., et al. 1998. Genomics. 53: 410-2. PMID: 9799612

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    ZNF207 Antibody (A-7)

    sc-271277
    200 µg/ml
    $322.00

    ZNF207 Antibody (A-7): m-IgG Fc BP-HRP Bundle

    sc-537602
    200 µg Ab; 10 µg BP
    $361.00

    ZNF207 Antibody (A-7): m-IgGκ BP-HRP Bundle

    sc-534913
    200 µg Ab; 40 µg BP
    $361.00

    ZNF207 Antibody (A-7): m-IgG1 BP-HRP Bundle

    sc-545255
    200 µg Ab; 20 µg BP
    $361.00

    Can ZNF207 (A-7): sc-271277 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: Randy McDonald
    Thank you for your question. Yes, ZNF207 (A-7): sc-271277 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced beautiful immunoperoxidase nuclearProduced beautiful immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human adrenal gland tissue. -SCBT QC
    Date published: 2015-01-21
    Rated 5 out of 5 by from Good Western Blot data of ZNF207 expressionGood Western Blot data of ZNF207 expression in HeLa nuclear extract and Hep G2 whole cell lysate . -SCBT QC
    Date published: 2014-08-31
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    ZNF207 Antibody (A-7) is rated 5.0 out of 5 by 2.
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