Ziprasidone hydrochloride monohydrate (CAS 138982-67-9)

모습 :

Powder

건강 상태 :

Solid

용해도 :

Soluble in DMSO (>10 mg/ml), DMF (~0.16 mg/ml), and 1: 2 solution of DMSO: PBS (pH 7.2) (~0.33 mg/ml). Insoluble in water.

저장 :

Store at room temperature

녹는점 :

>300° C

비등점 :

554.8° C at 760 mmHg (Predicted)

굴절률 :

n²⁰_D 1.75 (Predicted)

IC50 :

SR-2A: IC₅₀ = 0.42 nM (human); D2DR: IC₅₀ = 5 nM (human); Adrenergic receptor α-1: IC₅₀ = 11 nM (human); HERG: IC₅₀ = 120.23 nM (human); Histamine H1 receptor: IC₅₀ = 150 nM (rat)

Ki 데이타 :

SR-2A: K_i= 0.08 nM (human); Dopamine D2 receptor and Serotonin 2a receptor: K_i= 0.42 nM (rat); α-1a adrenergic receptor: K_i= 0.5 nM (rat); 5-HT1A agonist: K_i= 3.4 nM; D2 receptor: K_i= 4.8 nM

WGK 독일 :

3

PubChem CID :

Merck 색인 :

14: 10171

MDL 번호 :

MFCD00921885

SMILES :

C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.Cl