Zimelidine dihydrochloride CAS: 61129-30-4
MF: C16H17BrN2•2HCl
MW: 390.15
A selective 5-HT uptake inhibitor.

Zimelidine dihydrochloride (CAS 61129-30-4)

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Alternate Names: (2Z)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyrindinyl)-2-propen-1-amine dihydrochloride
Application Zimelidine dihydrochloride is a selective 5-HT uptake inhibitor
CAS 등록번호: 61129-30-4
분자량: 390.15
분자식: C16H17BrN22HCl
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* 참조분석증명서대량의 측정 데이터(함수량포함).

Zimelidine dihydrochloride is a selective 5-HT uptake inhibitor; selective over noradrenalin and dopamine uptake (IC50 values are 0.33, 8.2 and 12 μM respectively).


References

1. Ogren, S.O., et al. 1981. Acta Psychiatr. Scand. Suppl. 290: 127-151.
2. Fasmer, O.B., et al. 1987. Neuropharmacology. 26: 309-312.
3. Sugimoto, Y., et al. 1999. Biol. Pharm. Bull. 22: 1240-1241.

Physical State :
Solid
용해도 :
Soluble in water (100 mM), and 0.1M HCl (45 mg/ml).
저장 :
Desiccate at room temperature
굴절률 :
n20D 1.60 (Predicted)
IC50 :
Rattus norvegicus: IC50 = 100 nM; Mus musculus: IC50 = 1.7 µM; Serotonin transporter: IC50 = 4.5 µM (rat); Norepinephrine transporter: IC50 = 6.1 µM (rat); Plasmodium falciparum: IC50 = 6.31 µM
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
RTECS :
UC6555000
PubChem CID :
Merck Index :
14: 10126
MDL Number :
MFCD00069358
SMILES :
CN(C)CC=C(C1=CC=C(C=C1)Br)C2=CN=CC=C2.Cl.Cl

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분석증명서

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