Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. Proteins that contain WD-repeats participate in a wide range of cellular functions, however they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR77 (WD-repeat domain 77), also known as MEP50, is a 342 amino acid protein that contains five WD-repeats and is thought to regulate the early assembly of U snRNPs. Additionally, WDR77 functions as a component of a PRMT5-containing methyltransferase complex that converts arginines to dimethylarginines in a variety of spliceosomal Sm proteins. This conversion subsequently targets Sm proteins to the survival of motor neurons (SMN) complex where they are assembled into ribonucleoprotein core particles. Based on its involvement with the methyltransferase complex, WDR77 is thought to be involved in the development of testicular tumors, suggesting a role in carcinogenesis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.