Molecular structure of TRO 19622, CAS Number: 22033-87-0
TRO 19622 (CAS 22033-87-0)
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Alternate Names:
Olesoxime; Cholest-4-en-3-one oxime
Application:
TRO 19622 is a neuroregenerative and neuroprotective compound
CAS Number:
22033-87-0
Purity:
>98%
Molecular Weight:
399.65
Molecular Formula:
C27H45NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Neuroregenerative and neuroprotective compound. Promotes nerve regeneration following sciatic nerve crush in vivo and rescues motor neurons from axotomy-induced cell death. Binds directly to two components of the mitochondrial permeability pore, the voltage-dependent anion channel (VDAC) and translocator protein.
TRO 19622 (CAS 22033-87-0) References
Bordet et al (2007) Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. J.Pharmacol.Exp.Ther. 322 709.Inhibitor of:
OPA1.Activator of:
Cyclophilin C, and SMN.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRO 19622, 10 mg | sc-204356 | 10 mg | $119.00 | |||
TRO 19622, 50 mg | sc-204356A | 50 mg | $468.00 |