Trinactin CAS: 7561-71-9
MF: C43H70O12
MW: 779.0
A hydrophobic cyclic ester that acts as a macrotetrolide antibiotic.

Trinactin (CAS 7561-71-9)

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Application Trinactin is a hydrophobic cyclic ester that acts as a macrotetrolide antibiotic
CAS 등록번호: 7561-71-9
순도: >95%
분자량: 779.0
분자식: C43H70O12
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* 참조분석증명서대량의 측정 데이터(함수량포함).
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Trinactin is a hydrophobic cyclic ester that acts as a macrotetrolide antibiotic, isolated from Streptomyces aureus. Steady-state ion transport studies demonstrate that Trinactin behaves as an univalent cation cyclicly carrier. Trinactin has been shown to block incorporation of 3H-thymidine into lymphocytes treated with Concanavalin A (sc-203007) and is a homolog of Nonactin (sc-203164). Additionally, metabolic studies show that Trinactin has induced damped oscillatory mitochondrial swelling.


References

1. Meyers, E., et al. 1965. J. Antibiot. 18: 128-129. PMID: 14336167
2. Hladky, S.B. 1975. Biochim. Biophys. Acta. 375: 350-362. PMID: 1173049
3. Hertz, M.M., et al. 1977. Acta Physiol. Scand. 101: 501-503. PMID: 596227
4. Laprade, R., et al. 1984. Can. J. Biochem. Cell Biol. 62: 738-751. PMID: 6498590
5. Tanouchi, Y., et al. 1987. Jpn. J. Ophthalmol. 31: 218-229. PMID: 3499534

Appearance :
Film
Physical State :
Solid
에서 유래된 :
Streptomyces sp.
용해도 :
Soluble in ethyl acetate, DMSO, 100% ethanol (moderately ), and methanol (moderately ).
저장 :
Store at -20° C
비등점 :
909.68° C at 760 mmHg (Predicted)
밀도 :
1.02 g/cm3 (Predicted)
굴절률 :
n20D 1.45 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PubChem CID :
MDL Number :
MFCD00950778

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