trans-Glutaconic Acid (CAS 628-48-8)
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trans-Glutaconic acid is utilized in research focused on metabolic pathways and enzyme kinetics, particularly those involving the tricarboxylic acid cycle and amino acid metabolism. This compound serves as a substrate or inhibitor in various enzymatic reactions, allowing researchers to dissect the mechanisms underlying enzyme function and regulation. In addition to its biochemical applications, trans-Glutaconic acid is used in organic synthesis to explore and develop new synthetic routes for producing complex organic molecules. Its dicarboxylic acid structure makes it a versatile building block for synthesizing polymers and other macromolecules. Furthermore, trans-Glutaconic acid plays a role in studies related to energy production and storage, providing insights into more efficient ways to manage and utilize energy in biological systems.
trans-Glutaconic Acid (CAS 628-48-8) References
- Potassium hydrogen trans-glutaconate monohydrate at 295, 245 and 40 K, and its rubidium analogue at 298 K. | Kashino, S., et al. 2001. Acta Crystallogr C. 57: 549-52. PMID: 11353246
- Hydrogen-bonded complexes of 2-pyridone with centrosymmetric and non-centrosymmetric dicarboxylic acids. | Kashino, S., et al. 2001. Acta Crystallogr C. 57: 627-31. PMID: 11353274
- Identification of the gene and characterization of the activity of the trans-aconitate methyltransferase from Saccharomyces cerevisiae. | Cai, H., et al. 2001. Biochemistry. 40: 13699-709. PMID: 11695919
- Comparative supramolecular chemistry of coronene, hexahelicene, and [18]crown-6: hydrated and solvated molecular complexes of [18]crown-6 with 5-hydroxyisophthalic acid and related di- and tricarboxylic acids. | Ermer, O. and Neudörfl, J. 2001. Chemistry. 7: 4961-80. PMID: 11763465
- Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction. | Wimalasena, DS., et al. 2002. Biochem J. 367: 77-85. PMID: 12038965
- On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1. | Lund, TM., et al. 2004. J Neurosci Res. 77: 143-7. PMID: 15197747
- High-performance liquid chromatographic determination of xanthohumol in rat plasma, urine, and fecal samples. | Avula, B., et al. 2004. J Chromatogr Sci. 42: 378-82. PMID: 15355578
- Neurotoxic effects of trans-glutaconic acid in rats. | Schuck, PF., et al. 2013. Oxid Med Cell Longev. 2013: 607610. PMID: 23606926
- Adiabatic quantum computing with spin qubits hosted by molecules. | Yamamoto, S., et al. 2015. Phys Chem Chem Phys. 17: 2742-9. PMID: 25501117
- Dereplication-guided isolation of depsides thielavins S-T and lecanorins D-F from the endophytic fungus Setophoma sp. | de Medeiros, LS., et al. 2015. Phytochemistry. 111: 154-62. PMID: 25586883
- Unsaturated C3,5,7,9-Monocarboxylic Acids by Aqueous, One-Pot Carbon Fixation: Possible Relevance for the Origin of Life. | Scheidler, C., et al. 2016. Sci Rep. 6: 27595. PMID: 27283227
- One-pot formation of 2,4-di- or 2,4,6-tri-olefinic monocarboxylic acids by straight chain C4-extension. | Sobotta, J., et al. 2017. Heliyon. 3: e00368. PMID: 28795165
- Mechanochemical P-derivatization of 1,3,5-Triaza-7-Phosphaadamantane (PTA) and Silver-Based Coordination Polymers Obtained from the Resulting Phosphabetaines. | Udvardy, A., et al. 2020. Molecules. 25: PMID: 33207789
- The reaction of beta-chloroglutamic acid with glutamate-aspartate transaminase. | Manning, JM., et al. 1968. Eur J Biochem. 5: 199-208. PMID: 5667355
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
trans-Glutaconic Acid, 5 g | sc-489575 | 5 g | $240.00 |