Date published: 2026-5-21

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Tetramethylrhodamine ethyl ester perchlorate (CAS 115532-52-0)

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Alternate Names:
TMRE
Application:
Tetramethylrhodamine ethyl ester perchlorate is a mitochondrial potential-sensitive probe
CAS Number:
115532-52-0
Molecular Weight:
514.95
Molecular Formula:
C26H27ClN2O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetramethylrhodamine ethyl ester perchlorate is a fluorescent probe which is used in measuring membrane potential changes in mitochondria.Tetramethylrhodamine ethyl ester perchlorate (TMR-EP) is a versatile fluorescent dye employed in various scientific research areas. This water-soluble and non-toxic compound exhibits remarkable stability, making it ideal for a range of applications including fluorescence microscopy, and flow cytometry. esearchers frequently employ Tetramethylrhodamine ethyl ester perchlorate to label proteins and other molecules, enabling investigations into their structure, dynamics, and interactions. Furthermore, Tetramethylrhodamine ethyl ester perchlorate acts as a fluorescent label for proteins, binding to them and emitting light upon excitation by the appropriate wavelength of light.


Tetramethylrhodamine ethyl ester perchlorate (CAS 115532-52-0) References

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  2. Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis.  |  Hofmanová, J., et al. 2005. Cancer Lett. 218: 33-41. PMID: 15639338
  3. Respiration in adipocytes is inhibited by reactive oxygen species.  |  Wang, T., et al. 2010. Obesity (Silver Spring). 18: 1493-502. PMID: 20035277
  4. High glucose disrupts mitochondrial morphology in retinal endothelial cells: implications for diabetic retinopathy.  |  Trudeau, K., et al. 2010. Am J Pathol. 177: 447-55. PMID: 20522647
  5. ABC transporters affect the detection of intracellular oxidants by fluorescent probes.  |  Procházková, J., et al. 2011. Free Radic Res. 45: 779-87. PMID: 21568630
  6. Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells.  |  Plotegher, N., et al. 2014. Biochim Biophys Acta. 1840: 2014-24. PMID: 24561157
  7. Cardiomyocyte H9c2 cells present a valuable alternative to fish lethal testing for azoxystrobin.  |  Rodrigues, ET., et al. 2015. Environ Pollut. 206: 619-26. PMID: 26319055
  8. β Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice.  |  Rui, J., et al. 2017. Cell Metab. 25: 727-738. PMID: 28190773
  9. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma.  |  Shi, Y., et al. 2019. Nature. 567: 341-346. PMID: 30842654
  10. PDH-mediated metabolic flow is critical for skeletal muscle stem cell differentiation and myotube formation during regeneration in mice.  |  Hori, S., et al. 2019. FASEB J. 33: 8094-8109. PMID: 30939245
  11. Heterozygous variants in CTR9, which encodes a major component of the PAF1 complex, are associated with a neurodevelopmental disorder.  |  Meuwissen, M., et al. 2022. Genet Med. 24: 1583-1591. PMID: 35499524
  12. High glucose alters mitochondrial morphology and membrane potential heterogeneity in retinal endothelial cells  |  Trudeau, K., Molina, A., & Roy, S. 2009. Investigative Ophthalmology & Visual Science. 50(13): 33-33.
  13. MP34-05 N-METHYL-4-ISOLEUCINE CYCLOSPORINE, AN INHIBITOR OF MITOCHONDRIAL CYCLOPHILIN D ACTIVATION, PREVENTS KIDNEY STONE FORMATION BY ALLEVIATING OXIDATIVE STRESS IN RENAL TUBULAR CELLS  |  Yasui, T., Niimi, K., Okada, A., Taguchi, K., Fujii, Y., Hirose, Y.,.. & Kohri, K. 2015. The Journal of Urology. 193(4S): e411-e412.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetramethylrhodamine ethyl ester perchlorate, 25 mg

sc-213026
25 mg
$126.00