Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. Succinylacetone was developed to create a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine, wherein using a 13C4-SA as an internal standard. For the quantification of Succinylacetone from Plasmodium falciparum cultures, Succinylacetone is used as a standard. Succinylacetone is a component of dendritic cell conditioning medium. In the inhibition of ALA dehydratase (ALAD) in dendritic cells, Succinylacetone is also a component.
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