RT1-A Antibody (MN4-91-6): sc-59355

RT1-A Antibody (MN4-91-6) is a mouse monoclonal IgG1 antibody that detects RT1-A in mouse and rat samples through applications such as flow cytometry (FCM) and enzyme-linked immunosorbent assay (ELISA). RT1-A molecules, which encompass both class Ia and class Ib major histocompatibility complex (MHC I) proteins, play a crucial role in the immune response by presenting non-self peptides on the cell surface for recognition by cytotoxic T-lymphocytes (CTLs). These molecules are composed of two polypeptide chains: an alpha or heavy chain and beta-2-microglobulin, which is a non-covalently associated protein. The structure of RT1-A allows for the binding of antigenic peptides, typically 8-10 residues in length, within a specialized peptide binding groove. This structural feature is essential for the effective presentation of antigens to CTLs, thereby facilitating the immune system′s ability to identify and eliminate infected or malignant cells. RT1-A (MN4-91-6) antibody serves as an invaluable tool for researchers studying immune responses and MHC interactions in various biological contexts.

The preferred RT1-A antibody is RT1-A Antibody (OX18): sc-53074.