RAP55 Antibody (H-8): sc-390086
- RAP55 Antibody (H-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 41-75 near the N-terminus of RAP55 of human origin
- recommended for detection of RAP55 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, porcine and avian
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for RAP55 Antibody (H-8) for WB applications. These reagents are now offered in bundles with RAP55 Antibody (H-8) (see ordering information below).
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SEE ALSO...
RAP55 Antibody (H-8) is a mouse monoclonal IgG1 antibody that detects RAP55 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RAP55, also known as LSM14A, is a 463 amino acid protein that plays a crucial role in RNA metabolism and is essential for the formation of processing bodies (P-bodies), which are involved in mRNA decay and storage. RAP55 contains a FFD-TFG box domain and features an Sm-like motif, which is vital for interaction with other Sm-like proteins, contributing to the assembly of tri-snRNP particles necessary for pre-mRNA splicing. Notably, RAP55 undergoes phosphorylation in response to DNA damage, likely mediated by ATM or ATR kinases, highlighting involvement in cellular stress responses. The gene encoding RAP55 is conserved across a wide range of species, including chimpanzees, dogs, cows, and various model organisms, and is located on human chromosome 19q13.11. With RAP55′s ability to interact with specific proteins involved in RNA processing, anti-RAP55 antibody (H-8) serves as an invaluable tool for researchers studying gene expression and RNA regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RAP55 Antibody (H-8) | sc-390086 | 200 µg/ml | $322.00 | |||
RAP55 Antibody (H-8): m-IgG Fc BP-HRP Bundle | sc-540755 | 200 µg Ab; 10 µg BP | $361.00 | |||
RAP55 Antibody (H-8): m-IgG1 BP-HRP Bundle | sc-542350 | 200 µg Ab; 20 µg BP | $361.00 | |||
RAP55 (H-8) Neutralizing Peptide | sc-390086 P | 100 µg/0.5 ml | $69.00 |