PtdIns-(3)-P1 (1,2-dipalmitoyl) (ammonium salt) MF: C41H85N2O16P2
MW: 925.1

PtdIns-(3)-P1 (1,2-dipalmitoyl) (ammonium salt)

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Alternate Names: DPPI-3-P1; 1-(1,2-dihexadecanoylphosphatidyl)inositol-3-phosphate, diammonium salt
분자량: 925.1
분자식: C41H85N2O16P2
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* Refer to Certificate of Analysis for lot specific data (including water content).

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids but they play a crucial role in the generation and transmission of cellular signals. PtdIns-(3)-P1 can be further phosphorylated to give triphosphates such as PtdIns-(3,4,5)-P3. These can also be cleaved by PI-specific phospholipase C (PLC) to give inositol triphosphates (IP3). The diacyl glycerol and IP3 generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated.


References

1. Lapetina, E.G., et al. 1981. Nature. 292: 367-369. PMID: 626579
2. Majerus, P.W. 1992. Annu. Rev. Biochem. 61: 225-250. PMID: 1323235
3. Pike, L.J. and Casey, L. 1996. J. Biol. Chem. 271: 26453-26456. PMID: 8900109
4. Berridge, M.J. 1993. Nature. 361: 315-325. PMID: 8381210

Appearance :
Lyophilized powder
Physical State :
Solid
저장 :
Store at -20° C
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

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