Date published: 2025-9-8

001 800-1338-3838

SCBT Portrait Logo
Seach Input

PSGL-1 항체 (HECA-452): sc-53514

4.5(4)
리뷰 쓰기질문하기

데이터 시트
  • PSGL-1 항체 HECA-452 는 랫드 monoclonal IgM, 1간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • human 기원의 피부 호밍 메모리 세포에 대해 양성 반응
  • WB, IP, IF, IHC(P)와 FCM으로 mouse, rat와 human origin의 PSGL-1을 검출할것을 권장합니다.; skin-homing memory T cells, binding to the T cell carbohydrate ligand for vascular E-selectin 감지에 권장됨; 시아릴루이스 x와 시아릴루이스 a, 그리고 E-셀렉틴에 결합하는 다른 탄수화물 리간드, 그리고 고내피정맥의 E-셀렉틴 결합 에피토프를 인식합니다.
  • IF, IHC(P) 와 FCM에 사용가능한 phycoerythrin or fluoroscein 결합제품이 있습니다.
  • 현재 PSGL-1 항체(HECA-452)에 대해 선호하는 2차 검출 시약의 식별을 아직 완료하지 못했습니다. 이 작업은 진행 중입니다.

빠른 링크

더보기

PSGL-1(P-셀렉틴 당단백질 리간드, CD162라고도 함)은 이황화 결합된 호모다이머로 존재합니다. PSGL-1은 백혈구의 미세 융모 끝에 국한되는 1형 막 단백질입니다. 세포 외 도메인에는 세린, 트레오닌, 프롤린이 풍부하며, HL-60 및 U-937 세포와 인간 백혈구에서 각각 15개와 16개의 데카메릭 반복을 포함합니다. PSGL-1은 인간 조혈 세포에서 P-셀렉틴의 유일한 수용체처럼 보이지만, 독특한 결합 부위를 통해 E-셀렉틴과도 상호 작용합니다. PSGL-1이 E-셀렉틴 또는 P-셀렉틴에 결합하기 위해서는 PSGL-1이 시알릴화 및 푸코실화되어야 합니다. PSLG-1은 뮤신 유사 분자로서 류코시알린(CD43), CD164 및 CD34와 매우 유사합니다. 이 단백질은 조혈 세포에서 음성 신호를 전달하는 시알로뮤신이라는 새로운 세포 부착 수용체 계열에 속합니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

PSGL-1 항체 (HECA-452)

sc-53514
200 µg/ml
$316.00

PSGL-1 항체 (HECA-452) FITC

sc-53514 FITC
200 µg/ml
$330.00

PSGL-1 항체 (HECA-452) PE

sc-53514 PE
200 µg/ml
$343.00

I have a question regarding sc-53514. This is a rat monoclonal IgM. Would you be able to suggest a HRP conjugated secondary antibody for this product? I was wondering if I need anti rat anti IgM as secondary antibody or any anti Rat IgG will work for this

Asked by: AAAA2222
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-05-10

Can PSGL-1 (HECA-452): sc-53514 monoclonal antibody be used in WB with pig tissue or cells?

Asked by: nigel
Thank you for your question. This antibody has not yet been tested in pig samples and so that is not a recommended species at this time. We are still gathering data to show on our website. Check back for updates!
Answered by: Tech Service
Date published: 2019-11-13

Can PSGL-1 (HECA-452): sc-53514 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: AbPolly
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, PSGL-1 (HECA-452): sc-53514 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_29, h_8CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_3
  • loc_ko_KR, sid_53514, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 177ms
  • QUESTIONS, PRODUCT
Rated 3 out of 5 by from sc-53514I have a question regarding sc-53514. This is a rat monoclonal IgM. Would you be able to suggest a HRP conjugated secondary antibody for this product? I was wondering if I need anti rat anti IgM as secondary antibody or any anti Rat IgG will work for this purpose?
Date published: 2022-05-09
Rated 5 out of 5 by from nice IP stainingWe used this antibody for Immunoperoxidase staining and were able to get nice images of the stained areas
Date published: 2017-02-06
Rated 5 out of 5 by from Produced beautiful immunoperoxidase cytoplasmicProduced beautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human seminal vesicle tissue. -SCBT QC
Date published: 2015-01-20
Rated 5 out of 5 by from Superb indirect FCM data of human peripheralSuperb indirect FCM data of human peripheral blood leukocytes stained with PSGL-1 . -SCBT QC
Date published: 2014-09-06
  • y_2025, m_8, d_29, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_ko_KR, sid_53514, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT
PSGL-1 항체 (HECA-452) is rated 4.5 out of 5 by 4.
  • y_2025, m_8, d_29, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_ko_KR, sid_53514, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 108ms
  • REVIEWS, PRODUCT