PGM 2 Antibody (F-12): sc-376718
- PGM 2 Antibody (F-12) is a mouse monoclonal IgG2a κ PGM 2 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 503-533 near the C-terminus of PGM 2 of human origin
- PGM 2 Antibody (F-12) is recommended for detection of PGM 2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-PGM 2 Antibody (F-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PGM 2 Antibody (F-12) for WB applications. These reagents are now offered in bundles with PGM 2 Antibody (F-12) (see ordering information below).
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PGM 2 Antibody (F-12) is a mouse monoclonal IgG2a kappa light chain antibody that detects PGM 2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PGM 2 (F-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PGM 2 protein, consisting of 612 amino acids, is a member of the phosphoglucomutase family and plays a crucial role in carbohydrate metabolism, specifically in glycogenolysis and glycogenesis. PGM 2 protein catalyzes the interconversion of glucose-1-phosphate and glucose-6-phosphate, thereby facilitating energy production and storage. PGM 2 protein is predominantly localized in the cytoplasm of cells in tissues such as the lung, spleen, and thymus, which is significant for involvement in metabolic processes and potential implications in congenital immunodeficiencies. PGM 2 expression in these tissues suggests importance in maintaining cellular energy homeostasis and immune function, making PGM 2 protein a valuable target for research in metabolic disorders and immune system-related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PGM 2 Antibody (F-12) References:
- Mapping recombination hotspots in human phosphoglucomutase (PGM1). | Yip, SP., et al. 1999. Hum Mol Genet. 8: 1699-706. PMID: 10441333
- Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine development. | Buchanan, JT., et al. 2005. Infect Immun. 73: 6935-44. PMID: 16177373
- Overexpression of Mycobacterium tuberculosis manB, a phosphomannomutase that increases phosphatidylinositol mannoside biosynthesis in Mycobacterium smegmatis and mycobacterial association with human macrophages. | McCarthy, TR., et al. 2005. Mol Microbiol. 58: 774-90. PMID: 16238626
- Lithium induces phosphoglucomutase activity in various tissues of rats and in bipolar patients. | Csutora, P., et al. 2006. Int J Neuropsychopharmacol. 9: 613-9. PMID: 16259646
- Improvement of galactose uptake in Saccharomyces cerevisiae through overexpression of phosphoglucomutase: example of transcript analysis as a tool in inverse metabolic engineering. | Bro, C., et al. 2005. Appl Environ Microbiol. 71: 6465-72. PMID: 16269670
- Increased phosphoglucomutase activity suppresses the galactose growth defect associated with elevated levels of Ras signaling in S. cerevisiae. | Howard, SC., et al. 2006. Curr Genet. 49: 1-6. PMID: 16292676
- Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family. | Maliekal, P., et al. 2007. J Biol Chem. 282: 31844-51. PMID: 17804405
- A phylogeny for the principal alleles of the human phosphoglucomutase-1 locus. | Takahashi, N., et al. 1982. Proc Natl Acad Sci U S A. 79: 6636-40. PMID: 6216484
- Intragenic recombination at the human phosphoglucomutase 1 locus: predictions fulfilled. | Takahashi, N. and Neel, JV. 1993. Proc Natl Acad Sci U S A. 90: 10725-9. PMID: 7902567
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PGM 2 Antibody (F-12) | sc-376718 | 200 µg/ml | $322.00 | |||
PGM 2 Antibody (F-12): m-IgGκ BP-HRP Bundle | sc-523061 | 200 µg Ab, 40 µg BP | $361.00 | |||
PGM 2 Antibody (F-12): m-IgG2a BP-HRP Bundle | sc-546137 | 200 µg Ab; 10 µg BP | $361.00 | |||
PGM 2 Antibody (F-12) AC | sc-376718 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PGM 2 Antibody (F-12) HRP | sc-376718 HRP | 200 µg/ml | $322.00 | |||
PGM 2 Antibody (F-12) FITC | sc-376718 FITC | 200 µg/ml | $336.00 | |||
PGM 2 Antibody (F-12) PE | sc-376718 PE | 200 µg/ml | $349.00 | |||
PGM 2 Antibody (F-12) Alexa Fluor® 488 | sc-376718 AF488 | 200 µg/ml | $364.00 | |||
PGM 2 Antibody (F-12) Alexa Fluor® 546 | sc-376718 AF546 | 200 µg/ml | $364.00 | |||
PGM 2 Antibody (F-12) Alexa Fluor® 594 | sc-376718 AF594 | 200 µg/ml | $364.00 | |||
PGM 2 Antibody (F-12) Alexa Fluor® 647 | sc-376718 AF647 | 200 µg/ml | $364.00 | |||
PGM 2 Antibody (F-12) Alexa Fluor® 680 | sc-376718 AF680 | 200 µg/ml | $364.00 | |||
PGM 2 Antibody (F-12) Alexa Fluor® 790 | sc-376718 AF790 | 200 µg/ml | $364.00 | |||
PGM 2 (F-12) Neutralizing Peptide | sc-376718 P | 100 µg/0.5 ml | $69.00 |