Date published: 2025-9-8

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CD31/PECAM-1 항체 (JC70): sc-53411

4.9(10)
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데이터 시트
  • CD31/PECAM-1 항체(JC70) 는 마우스 monoclonal IgG1κ, 32간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • human의 비장에 대해 제기됨
  • CD31/PECAM-1 항체 (JC70)는 WB, IP, IF, IHC(P) and FCM으로 human유래의 PECAM-1 를 감지하는 데에 추천한다 .
  • 항-CD31/PECAM-1 항체(JC70)는 IP용 agarose와 결합되어 이용 가능하며, WB, IHC(P), ELISA용 HRP와 결합되어 이용 가능하며, IF, IHC(P), FCM용 phycoerythrin 또는 FITC와 결합되어 이용 가능합니다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • CD31/PECAM-1 (JC70): sc-53411무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP 는 CD31/PECAM-1 항체 (JC70) for WB and IHC(P) applications. 이 시약은 이제 CD31/PECAM-1 항체 (JC70)와 함께 번들로 제공됩니다(아래 주문 정보 참조).

빠른 링크

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PECAM-1 항체(JC70)는 웨스턴 블롯(WB), 면역침전법(IP), 면역형광법(IF), 파라핀 포매 섹션 면역조직화학(IHCP), 유세포분석법(FCM)을 통해 인간 PECAM-1을 검출하는 마우스 단일클론 IgG1 kappa 경쇄 항체입니다. 항-PECAM-1 항체(JC70)는 비접합 형태와 아가로스, 과산화효소(HRP), 피코에리트린(PE), 플루오레세인 이소티오시아네이트(FITC), 그리고 여러 알렉사 플루오르® 염료에 접합된 형태로 제공됩니다. CD31로도 알려진 PECAM-1은 단핵구, 호중구, 혈소판, 그리고 특정 T세포에 발현되는 중요한 당단백질로서, 면역 반응과 염증 동안 세포와 세포의 접착과 신호 전달에 중요한 역할을 합니다. PECAM-1은 주로 내피세포의 세포간 접합부에 위치해 있으며, 면역 감시 및 손상 반응에 필수적인 과정인 혈류에서 조직으로의 백혈구 이동을 촉진합니다. 또한 PECAM-1은 혈관 신생과 혈관 완전성 유지에 기여하며, 심혈관 질환 및 종양 생물학 연구에서 중요한 표지자 역할을 합니다. PECAM-1과 인테그린을 포함한 접착 분자의 상호 작용은 세포 통신 및 면역 반응 조절에서 그 중요성을 강조합니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

LI-COR®와 Odyssey®는 LI-COR Biosciences의 등록 상표입니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

CD31/PECAM-1 항체 (JC70)

sc-53411
200 µg/ml
$316.00

CD31/PECAM-1 (JC70): m-IgG Fc BP-HRP 번들

sc-526807
200 µg Ab; 10 µg BP
$354.00

CD31/PECAM-1 (JC70): m-IgG1 BP-HRP 번들

sc-532180
200 µg Ab; 20 µg BP
$354.00

CD31/PECAM-1 항체 (JC70) AC

sc-53411 AC
500 µg/ml, 25% agarose
$416.00

CD31/PECAM-1 항체 (JC70) HRP

sc-53411 HRP
200 µg/ml
$316.00

CD31/PECAM-1 항체 (JC70) FITC

sc-53411 FITC
200 µg/ml
$330.00

CD31/PECAM-1 항체 (JC70) PE

sc-53411 PE
200 µg/ml
$343.00

CD31/PECAM-1 항체 (JC70) Alexa Fluor® 488

sc-53411 AF488
200 µg/ml
$357.00

CD31/PECAM-1 항체 (JC70) Alexa Fluor® 546

sc-53411 AF546
200 µg/ml
$357.00

CD31/PECAM-1 항체 (JC70) Alexa Fluor® 594

sc-53411 AF594
200 µg/ml
$357.00

CD31/PECAM-1 항체 (JC70) Alexa Fluor® 647

sc-53411 AF647
200 µg/ml
$357.00

CD31/PECAM-1 항체 (JC70) Alexa Fluor® 680

sc-53411 AF680
200 µg/ml
$357.00

CD31/PECAM-1 항체 (JC70) Alexa Fluor® 790

sc-53411 AF790
200 µg/ml
$357.00

Is the epitope of this antibody extracellular?

Asked by: Luong
Thank you for your question. PECAM-1 Antibody (JC70): sc-53411 is raised against spleen of human origin. The exact epitope recognized by this mouse monoclonal antibody has not been determined, thus we do not know if it is extracellular or intracellular.
Answered by: Technical Support
Date published: 2017-04-13

Can PECAM-1 (JC70): sc-53411 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Professor Griffin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, PECAM-1 (JC70): sc-53411 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great Antibody for human blood vessels detectionThis antibody works perfectly to detect human CD31 in immunofluorescence on fixed frozen section. It gives little to none cross-reaction to mouse-origin vessels. Dilution 1:100 / incubation over night at 4°C.
Date published: 2022-08-03
Rated 5 out of 5 by from Excellent antibodyThis antibody works perfectly on human aortic endothelial cells. Our lab use this antibody to verify the phenotype of endothelial cells that we isolate ourselves from human aortic specimens. We incubate PFA-fixed cells with the primary antibody overnight at 4C (dilution 1/100) and obtain the expected staining pattern with fluorescence at the plasma membrane.
Date published: 2018-03-01
Rated 5 out of 5 by from GoodI was gifted friendly by other lab. and proceeded IF with a dilution factor of 1:50 in HUVEC as a positive control. It was good. The higher dilution factor also will be good I think.
Date published: 2017-02-12
Rated 5 out of 5 by from Excellent!This antibody is great in western blot analysis of PECAM-1 expression in Jurkat, CCRF-CEM and K-562 whole cell lysates.
Date published: 2017-01-26
Rated 5 out of 5 by from It has been reported that this antibody wasIt has been reported that this antibody was used successfully in immunocytochemistry with human ubendocardial MSCs. -SCBT Publication Review
Date published: 2015-04-23
Rated 5 out of 5 by from Worked well in immunohistochemistry usingWorked well in immunohistochemistry using formalin fixed human Jelly Mesenchymal Stem Cells. -SCBT Publication Review
Date published: 2015-04-12
Rated 5 out of 5 by from Publishable data obtained by flow cytometryPublishable data obtained by flow cytometry using human mononuclear cells. -SCBT Publication Review
Date published: 2015-01-13
Rated 5 out of 5 by from Produced good quality flow cytometry dataProduced good quality flow cytometry data using human stem cells. -SCBT Publication Review
Date published: 2015-01-05
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CD31/PECAM-1 항체 (JC70) is rated 4.9 out of 5 by 10.
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