See p57 Kip2 (KP39): sc-56341 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
m-IgG2b BP-HRP is the preferred secondary detection reagent for p57 Kip2 Antibody (3F245) for WB and IHC(P) applications. This reagent is now offered in a bundle with p57 Kip2 Antibody (3F245) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Cell cycle progression is regulated by a series of cyclin-dependent kinases that consist of catalytic subunits designated Cdks and activating subunits designated cyclins. Orderly progression through the cell cycle requires the activation and inactivation of different cyclin-Cdks at appropriate times. A series of proteins has been described that function as mitotic inhibitors. These include p21 Waf1/Cip1, the levels of which are elevated upon DNA damage in G1 in a p53-dependent manner; p16 INK4A; and p16 INK4A-related inhibitors, designated p15 INK4B, p18 INK4C and p19 INK4D. A p21 Waf1/Cip1-related protein, p27, has been described as a negative regulator of G1 progression and has been speculated to function as a possible mediator of TGFβ-induced G1 arrest. A member of the p21 Waf1/Cip1/p27 family of mitotic inhibitory proteins, p57 Kip2 (also designated p57 and Kip2), is a potent, tight-binding cyclin-dependent inhibitor of several G1 cyclin/Cdk complexes. Overexpression of p57 Kip2 arrests cells in G1. Unlike p21 Waf1/Cip1, p57 Kip2 is not regulated by p53.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.