NDV HN Antibody (IC114): sc-53563

NDV HN Antibody (IC114) is a mouse monoclonal IgG1 antibody that detects NDV HN protein of Newcastle disease virus by immunoprecipitation (IP) and immunofluorescence (IF) applications. NDV HN, or hemagglutinin neuraminidase, is a critical glycoprotein that plays a vital role in the viral life cycle by facilitating viral attachment to host cells. NDV HN protein is located on the external envelope of the virus and binds to sialic acid-containing receptors on target cell surfaces, which is essential for initiating infection. NDV HN protein interaction with these receptors promotes viral entry and triggers upregulation of host cell factors such as TRAIL and death receptors, influencing the immune response. The fusion of viral and cellular membranes, a process regulated by NDV F protein, is crucial for viral spread to neighboring cells, enhancing infectivity and virulence. Anti-NDV HN antibody (IC114) serves as an invaluable tool for researchers studying Newcastle disease virus infection mechanisms and host response, providing insights into potential therapeutic targets and strategies for disease control.

The preferred NDV HN antibody is NDV HN Antibody (HN14f): sc-53562.