Myristoyl coenzyme A Sodium Salt (CAS 3130-72-1)
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Myristoyl coenzyme A Sodium Salt, abbreviated as Myristoyl CoA, plays a pivotal role in various biochemical processes, particularly in the synthesis and degradation of lipids. This molecule is integral to the activation of fatty acids, where it acts as a substrate for acyl-CoA synthetase, facilitating the conversion of free fatty acids into their corresponding acyl-CoA derivatives. This transformation is for the subsequent metabolic pathways, including beta-oxidation and the biosynthesis of complex lipids such as phospholipids and triglycerides. In research applications, Myristoyl coenzyme A Sodium Salt is extensively utilized to study enzyme kinetics and substrate specificity, especially in investigations related to fatty acid metabolism. Its role in modulating the acylation status of proteins also makes it useful in studying protein function and regulation, which is key for understanding cellular signaling and energy homeostasis.
Myristoyl coenzyme A Sodium Salt (CAS 3130-72-1) References
- Development of an enzyme-linked immunosorbent assay for measurement of activity of myristoyl-coenzyme A:protein N-myristoyltransferase. | Takamune, N., et al. 2002. Anal Biochem. 309: 137-42. PMID: 12381372
- Aspergillus nidulans swoF encodes an N-myristoyl transferase. | Shaw, BD., et al. 2002. Eukaryot Cell. 1: 241-8. PMID: 12455958
- Myristoyl-CoA:protein N-myristoyltransferases: isoform identification and gene expression in retina. | Rundle, DR., et al. 2004. Mol Vis. 10: 177-85. PMID: 15041955
- Quantification of the concentration and 13C tracer enrichment of long-chain fatty acyl-coenzyme A in muscle by liquid chromatography/mass spectrometry. | Sun, D., et al. 2006. Anal Biochem. 349: 87-95. PMID: 16307720
- A peroxisomal acyltransferase in mouse identifies a novel pathway for taurine conjugation of fatty acids. | Reilly, SJ., et al. 2007. FASEB J. 21: 99-107. PMID: 17116739
- Synthesis of myristoyl-carba(dethia)-coenzyme A and S-(3-oxohexadecyl)-coenzyme A, two potent inhibitors of myristoyl-CoA:protein N-myristoyltransferase. | Wagner, AP. and Rétey, J. 1991. Eur J Biochem. 195: 699-705. PMID: 1999191
- Heterogeneous N-terminal acylation of retinal proteins results from the retina's unusual lipid metabolism. | Bereta, G. and Palczewski, K. 2011. Biochemistry. 50: 3764-76. PMID: 21449552
- A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes. | Gaffarogullari, EC., et al. 2011. J Mol Biol. 411: 823-36. PMID: 21740913
- A fluorescence-based assay for N-myristoyltransferase activity. | Goncalves, V., et al. 2012. Anal Biochem. 421: 342-4. PMID: 22051857
- A highly convergent synthesis of myristoyl-carba(dethia)-coenzyme A. | Tautz, L. and Rétey, J. 2010. European J Org Chem. 2010: 1728-1735. PMID: 22347809
- Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties. | Russo, SB., et al. 2013. J Biol Chem. 288: 13397-409. PMID: 23530041
- Histone Deacetylase 11 Is a Fatty-Acid Deacylase. | Kutil, Z., et al. 2018. ACS Chem Biol. 13: 685-693. PMID: 29336543
- Mapping the myristoylome through a complete understanding of protein myristoylation biochemistry. | Giglione, C. and Meinnel, T. 2022. Prog Lipid Res. 85: 101139. PMID: 34793862
- N-Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus. | Wang, Y., et al. 2023. Microbiol Spectr. 11: e0421222. PMID: 36541770
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myristoyl coenzyme A Sodium Salt, 10 mg | sc-286320 | 10 mg | $634.00 |