human origin의 MAG에서 N-terminus에 위치한 1-300 아미노산을 항원으로 사용하였습니다.
안티-MAG 항체 (A-11)는 WB, IP, IF, IHC(P) and ELISA으로 mouse, rat and human유래의 MAG 를 감지하는 데에 추천한다.
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-MAG 항체 (A-11)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for MAG Antibody (A-11) for WB and IHC(P) applications. These reagents are now offered in bundles with MAG Antibody (A-11) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MAG Antibody (A-11) is a high quality monoclonal MAG antibody (also designated Sialic Acid Binding Ig-Like Lectin 4A antibody, Myelin-Associated Glycoprotein antibody, SIGLEC-4A antibody, SIGLEC4A antibody, S-MAG antibody, GMA antibody, Sialic Acid-Binding Immunoglobulin-Like Lectin 4A antibody, Siglec-4a antibody, or SPG75 antibody) suitable for the detection of the MAG protein of mouse, rat and human origin. MAG Antibody (A-11) is available as both the non-conjugated anti-MAG antibody form, as well as multiple conjugated forms of anti-MAG antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Myelin-associated glycoprotein (MAG) is a nervous system cell-surface adhesion protein that is involved in linking myelinating glial cells to neuronal axons. MAG contains a sialic acid binding site and five IgG-like domains, thus identifying MAG as a member of a subgroup of the immunoglobulin superfamily. Like myelin, MAG inhibits axonal outgrowth and contributes to the inhibitory properties of myelin. Growth inhibition by MAG has been shown to be blocked when cerebellar neurons are pre-incubated with the neurotrophins BDNF or GDNF. It is suggested that this neurotrophin priming elevates cAMP and activates PKA.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences