human origin의 MACF1 isoform 4에서 에 가까운 1561-1780 아미노산을 항원으로 사용하였습니다.
MACF1-4 항체 (D-10)는 WB, IP, IF and ELISA으로 human유래의 MACF1 isoform 4 를 감지하는 데에 추천한다 .
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-MACF1-4 항체 (D-10)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MACF1-4 Antibody (D-10) for WB applications. These reagents are now offered in bundles with MACF1-4 Antibody (D-10) (see ordering information below).
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MACF1-4 Antibody (D-10) is a high quality monoclonal MACF1-4 antibody (also designated MACF1-4 antibody) suitable for the detection of the MACF1-4 protein of human origin. MACF1-4 Antibody (D-10) is available as both the non-conjugated anti-MACF1-4 antibody form, as well as multiple conjugated forms of anti-MACF1-4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. MACF1-4 (Microtubule-Actin cross-linking factor 1, isoform 4) is a 5,327 amino acid protein that is encoded by the human gene MACF1. MACF1-4 belongs to the plakin or cytolinker family and contains one Actin-binding domain, two CH (calponin-homology) domains, two EF-hand domains, nineteen plectin repeats and thirty-seven spectrin repeats. MACF1-4 is an F-Actin-binding protein which may play a role in cross-linking cytoskeletal proteins by binding intermediate filaments to the N-terminal plectin repeats and microtubules to the C-terminus. The spectrin repeats, an important feature found in many proteins involved in cytoskeletal structure, forms a three helix bundle with the second helix (with proline interrupts in some sequences). MACF1-4 is a cytoplasmic protein expressed mainly in heart, lung, pituitary and placenta; however, it is not found in brain, kidney, liver, pancreas or skeletal muscle.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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