KH CB19 CAS: 1354037-26-5
MF: C15H13Cl2N3O2
MW: 338.19
A potent and selective inhibitor of CDC2-like kinase (CLK) 1 and 4.

KH CB19 (CAS 1354037-26-5)

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Alternate Names: Ethyl 3-(2-Amino-1-cyanoethenyl)-6,7-dichloro-1-methylindole-2-carboxylate
Application KH CB19 is a potent and selective inhibitor of CLK1 and CLK4 (CDC2-like kinase 1 and 4)
CAS 등록번호: 1354037-26-5
순도: >97%
분자량: 338.19
분자식: C15H13Cl2N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

KH CB19 is a potent and selective inhibitor of CDC2-like kinase (CLK) 1 and 4. KH CB19 suppresses serine/arginine-rich protein phosphorylation by CLKs under proinflammatory conditions.

Physical State :
Solid
용해도 :
Soluble in DMSO (40 mM).
저장 :
Store at -20° C
비등점 :
~604.1° C at 760 mmHg (Predicted)
밀도 :
~1.4 g/cm3 (Predicted)
굴절률 :
n20D 1.62 (Predicted)
IC50 :
CLK1: IC50 = 20 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44237094
MDL Number :
MFCD20926346
SMILES :
CCOC(=O)C1=C(C2=C(N1C)C(=C(C=C2)Cl)Cl)/C(=C\N)/C#N

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