

H2-I/Abβ Antibody (5K40) is a mouse monoclonal IgM antibody that detects H2-I/Abβ in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). H2-I/Abβ plays a crucial role in the immune response by functioning as a component of the major histocompatibility complex (MHC) class II molecules, which are essential for presenting antigens to CD4+ T cells. This interaction is vital for the activation of T lymphocytes, which orchestrate the adaptive immune response. H2-I/Abβ is primarily located on the surface of antigen-presenting cells, including B cells, macrophages, and dendritic cells, where H2-I/Abβ binds to foreign peptides and facilitates their recognition by T cells. Proper functioning of H2-I/Abβ is critical for effective immune surveillance and response, as any dysfunction in this process can lead to inadequate immune activation or autoimmune diseases. Anti-H2-I/Abβ antibody (5K40) is an invaluable tool for researchers studying the intricacies of immune responses and the mechanisms of antigen presentation in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
H2-I/Abβ Antibody (5K40) | sc-71201 | 100 µg/ml | $322.00 |