Date published: 2025-9-7

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galectin-3 항체 (M3/38): sc-23938

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데이터 시트
  • galectin-3 항체 M3/38 는 랫드 monoclonal IgG2a, 59간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • 유전자침묵제품은 비영리적인용도나 연구에만 사용가능합니다 자세한 정보보기.
  • 안티-galectin-3 항체 (M3/38)는 WB, IP, IF and IHC(P)으로 mouse, rat and human유래의 Galectin-3 를 감지하는 데에 추천한다.
  • 항-galectin-3 항체(M3/38)는 IP용 agarose와 결합되어 이용 가능하며, WB, IHC(P), ELISA용 HRP와 결합되어 이용 가능하며, IF, IHC(P), FCM용 phycoerythrin 또는 FITC와 결합되어 이용 가능합니다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • galectin-3 (M3/38): sc-23938무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • 현재 galectin-3 항체(M3/38)에 대해 선호하는 2차 검출 시약의 식별을 아직 완료하지 못했습니다. 이 작업은 진행 중입니다.

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갈렉틴-3 항체(M3/38)는 갈렉틴-3을 표적으로 삼도록 설계된 쥐 단일 클론 IgG2a 항체로서, Mac-2, hMac-2(인간 Mac-2), GALBP(갈락토오스 결합 단백질), CBP35(탄수화물 결합 단백질 35), LGALS3(렉틴, 갈락토사이드 결합, 가용성, 3) 등의 다른 이름으로도 알려져 있습니다. 항갈렉틴-3 항체(M3/38)는 마우스에서 유래된 갈렉틴-3에 대해 생성되며, 웨스턴 블롯(WB), 면역침전법(IP), 면역형광법(IF), 파라핀 포매 섹션 면역조직화학법(IHCP)을 포함한 다양한 응용 방법을 통해 마우스, 쥐, 인간 샘플에서 갈렉틴-3을 검출하는 데 권장됩니다. 갈렉틴-3은 수용성 β-갈락토사이드 결합 렉틴의 갈렉틴 계열의 핵심 구성원으로서, 조직 발달, 면역 반응, 세포 간 통신과 같은 과정에 중요한 세포 간 접착과 세포와 세포 외 기질(ECM) 간의 상호작용을 조절하는 데 필수적인 역할을 합니다. 세포질과 핵의 세포 내, 그리고 ECM의 세포 외에 위치하는 갈렉틴-3의 세포 내 국소화는 다양한 기능에 매우 중요합니다. 세포 내에서는 신호 전달 경로, 전mRNA 스플라이싱, 세포 자멸에 관여하고, 세포 외에서는 세포 부착, 이동, 그리고 세포외기질과의 상호작용을 촉진합니다. 이러한 기능 때문에 세포 항상성 유지와 세포 스트레스에 대한 반응에 필수적인 역할을 합니다. 중요한 것은, 갈렉틴-3이 암세포 증식, 세포 자멸 저항성, 혈관 신생에 영향을 미치면서 종양 진행과 전이에 관여하기 때문에, 갈렉틴-3이 암 연구에서 중요한 표적이 된다는 것입니다. 갈렉틴-3(M3/38) 항체는 비접합 형태와 아가로스, 호스래디시 퍼옥시다아제(HRP), 피코에리트린(PE), 플루오레세인 이소티오시아네이트(FITC), 다양한 알렉사 플루오르® 접합체를 포함한 다중 접합체 형태로 제공되어 다양한 실험적 응용을 위한 다양한 옵션을 제공합니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

LI-COR®와 Odyssey®는 LI-COR Biosciences의 등록 상표입니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

galectin-3 항체 (M3/38)

sc-23938
200 µg/ml
$316.00

galectin-3 항체 (M3/38) AC

sc-23938 AC
500 µg/ml, 25% agarose
$416.00

galectin-3 항체 (M3/38) HRP

sc-23938 HRP
200 µg/ml
$316.00

galectin-3 항체 (M3/38) FITC

sc-23938 FITC
200 µg/ml
$330.00

galectin-3 항체 (M3/38) PE

sc-23938 PE
200 µg/ml
$343.00

galectin-3 항체 (M3/38) Alexa Fluor® 488

sc-23938 AF488
200 µg/ml
$357.00

galectin-3 항체 (M3/38) Alexa Fluor® 546

sc-23938 AF546
200 µg/ml
$357.00

galectin-3 항체 (M3/38) Alexa Fluor® 594

sc-23938 AF594
200 µg/ml
$357.00

galectin-3 항체 (M3/38) Alexa Fluor® 647

sc-23938 AF647
200 µg/ml
$357.00

galectin-3 항체 (M3/38) Alexa Fluor® 680

sc-23938 AF680
200 µg/ml
$357.00

galectin-3 항체 (M3/38) Alexa Fluor® 790

sc-23938 AF790
200 µg/ml
$357.00

Hello, can I confirm that this antibody recognizes an epitope on the the N-terminal of Gal-3? Thanks!

Asked by: Jun Ong
Thank you for your question. sc-23938 recognizes an epitope in the N-terminal.
Answered by: BlakeJ
Date published: 2024-10-03

Hello, can I confirm that this antibody recognizes an epitope on the the N-terminal (aa 40 - 100) of Gal-3? Thanks!

Asked by: Jun Ong
Thank you for your question. sc-23938 recognizes an epitope in the N-terminal. Here is a link for more information on the protein : https://www.uniprot.org/uniprotkb/P16110/entry
Answered by: BlakeJ
Date published: 2024-10-03

Que dilución es recomendable usar para WB en suero humano

Asked by: Mari30
Thank you for your question. Galectin-3 Antibody (M3/38): sc-23938 is recommended for detection of galectin-3 of mouse, rat and human origin by Western Blotting at a starting dilution 1:200 (general dilution range 1:100-1:1000)
Answered by: Tech Support Europe
Date published: 2024-09-17

I would like to stain galectin-3 on renal sections by IHC. Which demasking conditions do you recommend for this antibody (EDTA, citrate, etc.) ? Which dilution as well ?

Asked by: pierrelo
Thank you for your question. Our recommended method is as follows: Heat treatment: Place slides in a container and cover with 10 mM sodium citrate buffer, pH 6.0 (sc-294091); or with 50 mM glycine-HCl buffer (sc-29096), pH 3.5, with 0.01% (w/v) EDTA (sc-29092). Heat at 95° C for 5 minutes. Top off with fresh buffer and heat at 95° C for 5 minutes (optimal incubation time may vary for each tissue type). Allow slides to cool in the buffer for approximately 20 minutes. Wash in deionized H2O three times for 2 minutes each. Aspirate excess liquid from slides.
Answered by: Tech Support Europe
Date published: 2024-01-04

Is the antibody raised against the C or N-terminus of the protein?

Asked by: Maria93
Thank you for your question.The antibody is raised against the N-terminus.
Answered by: BlakeJ
Date published: 2023-08-30

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: cjMara
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 12
Date published: 2017-01-22

I need to use an antibody to detect the protein in samples of canine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Thank you for your question. We have not tested this antibody in canine samples, however this antibody clone has been published on dog samples (for example, PMID: 20705359). Please contact Technical Service by phone, (800)-457-3801 option 2, email <scbt@scbt.com>, or by live chat directly on our website, www.scbt.com if you have any further questions.
Answered by: Tech Service
Date published: 2017-01-12
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Rated 5 out of 5 by from Good for WB and IPThe antibody presents good staining for WB and also works for immunoprecipitation. Tested in human and rat cells.
Date published: 2024-08-23
Rated 5 out of 5 by from ExcellentIt works for IF nicely. Very bright signal was detected.
Date published: 2024-01-17
Rated 5 out of 5 by from Molto buono!Ho testato questo anticorpo per immunoistochimica su polmoni di topo in paraffina perché stavo cercando un marcatore alternativo per l'identificazione dei macrofagi. La colorazione risulta essere chiara e pulita e sembra ben identificare i macrofagi alveolari.
Date published: 2021-04-13
Rated 5 out of 5 by from Great FeaturesI got the sample antibody a month ago and I probed the lysates for the galectin 3 expression. The bands were good even at 1:400 dilution. The original recommended dilution in the SDS was 1:100
Date published: 2019-09-16
Rated 5 out of 5 by from galectin 3 antibody (sample) recomendableAB sample was tested for IF (1/50) and gave perfect results! Highly recommended since it gave very nice pictures. Will order it.
Date published: 2018-04-11
Rated 5 out of 5 by from Wow !! Superb product !Really strong western blot data; also outstanding IHC !!
Date published: 2017-01-31
Rated 5 out of 5 by from Excellent rat monoclonalThere are several very good galectin-3 clones to choose from, however this galectin-3 (M3/38) clone provides an option of a rat host with excellent data in Western blot and IHC(P). Plus, this clone is featured in several recent publications!
Date published: 2017-01-30
Rated 4 out of 5 by from Publication in IF with mouse leg musclesPublication in IF with mouse leg muscles. -SCBT Publication Review
Date published: 2015-04-21
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galectin-3 항체 (M3/38) is rated 4.6 out of 5 by 12.
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