ERCC1 Antibody (3H11): sc-53281
- ERCC1 Antibody (3H11) is a mouse monoclonal IgG2a κ, cited in 10 publications, provided at 200 µg/ml
- raised against full length human ERCC1
- recommended for detection of ERCC1 of mouse, rat and human origin by WB, IP and ELISA
- See ERCC1 (D-10): sc-17809 for ERCC1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ERCC1 Antibody (3H11) for WB applications. These reagents are now offered in bundles with ERCC1 Antibody (3H11) (see ordering information below).
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SEE ALSO...
ERCC1 Antibody (3H11) is a mouse monoclonal IgG2a antibody that detects ERCC1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). ERCC1, also known as excision repair cross-complementing 1, plays a crucial role in the nucleotide excision repair pathway, which is essential for maintaining genomic stability by repairing DNA damage caused by ultraviolet light and other environmental factors. ERCC1 forms a heterodimer with XPF, another key player in this repair process, and together they function as a structure-specific endonuclease that incises damaged DNA. This incision is vital for the removal of bulky DNA adducts, thereby preventing mutations that could lead to skin cancer and other malignancies. The significance of ERCC1 in DNA repair highlights its potential as a biomarker for cancer susceptibility and treatment response, making anti-ERCC1 antibody (3H11) an invaluable tool for researchers studying DNA repair mechanisms and their implications in disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ERCC1 Antibody (3H11) | sc-53281 | 200 µg/ml | $322.00 | |||
ERCC1 Antibody (3H11): m-IgG Fc BP-HRP Bundle | sc-536927 | 200 µg Ab; 10 µg BP | $361.00 | |||
ERCC1 Antibody (3H11): m-IgGκ BP-HRP Bundle | sc-534102 | 200 µg Ab; 40 µg BP | $361.00 | |||
ERCC1 Antibody (3H11): m-IgG2a BP-HRP Bundle | sc-547901 | 200 µg Ab; 10 µg BP | $361.00 |