Date published: 2025-9-7

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DHFR 항체 (A-4): sc-74593

4.3(4)
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데이터 시트
  • DHFR 항체(A-4) 는 마우스 monoclonal IgG2aκ, 5간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • human origin의 DHFR의 1-187 아미노산을 항원으로 사용하였습니다.
  • WB, IP, IF와 ELISA으로 mouse, rat와 human origin의 DHFR을 검출할것을 권장합니다.
  • See DHFR (A-9): sc-377091 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • 2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP는 DHFR 항체 (A-4) WB 애플리케이션용입니다. 이 시약은 이제 DHFR 항체 (A-4)와 함께 번들로 제공됩니다(아래 주문 정보 참조).

빠른 링크

더보기

디하이드로폴레이트 환원효소(DHFR)는 디하이드로폴레이트를 테트라하이드로폴레이트로의 NADPH 의존적 환원을 촉매하며 퓨린, 피리미딘 및 일부 아미노산 합성에 중요한 효소입니다. 이 효소의 활성이 억제되면 DNA 합성이 중단되고 세포가 사멸합니다. 정상 조혈 세포에서 메토트렉세이트(MTX) 내성 변이 DHFR의 유전자 발현은 약물에 민감한 정상 세포와 조직에서 약물 독성을 완화하여 더 많은 용량의 MTX를 투여할 수 있는 잠재적 전략입니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

DHFR 항체 (A-4)

sc-74593
200 µg/ml
$316.00

DHFR (A-4): m-IgGκ BP-HRP 번들

sc-534448
200 µg Ab; 40 µg BP
$354.00

DHFR (A-4): m-IgG2a BP-HRP 번들

sc-546190
200 µg Ab; 10 µg BP
$354.00

I need to use an antibody to detect the protein in samples of avian origin. Do you know if sc-74593: DHFR (A-4) mouse monoclonal antibody will work?

Asked by: Dr Ninau Qelp
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 5 out of 5 by from This primary antibody has superior specificityThis primary antibody has superior specificity and works at low concentrations/high dilutions with high success rate. Applicable for both recombinant protein expressed from E. coli and total plant extract from Arabidopsis thaliana expressing DHFR-containing constructs as transgenics.
Date published: 2016-09-26
Rated 4 out of 5 by from Strong bands seen in WB using HeLaStrong bands seen in WB using HeLa, Jurkat, Y79 and KNRK whole cell lysates. -SCBT QC
Date published: 2015-04-30
Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
Date published: 2015-03-27
Rated 4 out of 5 by from Band seen in WB using human recombinant DHFRBand seen in WB using human recombinant DHFR. -SCBT QC
Date published: 2014-10-22
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DHFR 항체 (A-4) is rated 4.3 out of 5 by 4.
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