human origin의 CRMP-5에서 내부에 위치한 369-564 아미노산을 항원으로 사용하였습니다.
안티-CRMP-5 항체 (CR-1)는 WB, IP and IF으로 mouse, rat, human and bovine유래의 the C terminal region of CRMP-5 를 감지하는 데에 추천한다.; other CRMP isoforms와 교차반응이 없습니다.
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-CRMP-5 항체 (CR-1)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CRMP-5 Antibody (CR-1) is a high quality monoclonal CRMP-5 antibody (also designated CRMP-5 antibody) suitable for the detection of the CRMP-5 protein of mouse, rat, human and bovine origin. CRMP-5 Antibody (CR-1) is available as both the non-conjugated anti-CRMP-5 antibody form, as well as multiple conjugated forms of anti-CRMP-5 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-5, which is phylogenetically divergent from the other four CRMPs, is expressed in the filopodia of growth cones as well as in adult central and peripheral neurons, including synapses. The paraneoplastic CRMP-5 autoantibody (CRMP-5-IgG) is also associated with small-cell lung carcinoma or thymoma.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences