raised against amino acids 1861-2140 mapping within an internal region of Collagen Type XII of human origin
COL12A1 항체 (A-11)는 WB, IP, IF and ELISA으로 human유래의 Collagen Type XII 를 감지하는 데에 추천한다 .
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-COL12A1 항체 (A-11)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
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COL12A1 Antibody (A-11) is a high quality monoclonal COL12A1 antibody (also designated COL12A1 antibody) suitable for the detection of the COL12A1 protein of human origin. COL12A1 Antibody (A-11) is available as both the non-conjugated anti-COL12A1 antibody form, as well as multiple conjugated forms of anti-COL12A1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Collagen Type XII is a 3,063 amino acid protein encoded by the human gene COL12A1. Collagen Type XII belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Collagen Type XII is known to interact with type I collagen-containing fibrils. The COL1 domain is thought to be associated with the surface of the fibrils, while the COL2 and NC3 domains may be localized in the perifibrillar matrix. Collagen Type XII has 3 identified isoforms (named 1, 2 and 4). Isoform 1 is the long form of the protein, while 2 and 4 are missing sequences found in isoform 1. Collagen Type XII is found in Collagen Type I-containing tissues: both isoform 1 and isoform 2 appear in amnion, chorion, skeletal muscle, small intestine and cell culture of dermal fibroblasts, keratinocytes and endothelial cells. Only isoform 2 is found in lung, placenta, kidney and a squamous cell carcinoma cell line. Isoform 1 is also present in the corneal epithelial Bowman′s membrane (BM) and the interfibrillar matrix of the corneal stroma, but it is not detected in the limbal BM.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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