beta Tubulin Antibody (3F3-G2): sc-53140

β Tubulin Antibody (3F3-G2) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect β Tubulin, also known as tubulin beta chain, across mouse, rat, and human species. β Tubulin monoclonal antibody (3F3-G2) is raised against brain extract of rat origin, ensuring strong and reliable binding in applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. β Tubulin is a fundamental component of the cytoskeleton, forming heterodimers with α Tubulin that polymerize into microtubules, which are essential for maintaining cell shape, enabling intracellular transport, and facilitating proper cell division. The structural integrity of β Tubulin, including its ability to bind and hydrolyze GTP, is crucial for the dynamic instability of microtubules, allowing cells to rapidly reorganize their cytoskeleton in response to various signals. This structural versatility makes β Tubulin indispensable for processes such as mitosis, intracellular trafficking, and the establishment of cell polarity. Additionally, β Tubulin exists in multiple isoforms, including β1, β2, β3, β4, β5, β6, and β8, each contributing uniquely to cellular functions and offering insights into tissue-specific roles and disease mechanisms. Understanding the precise structure of β Tubulin is vital for elucidating its role in cellular architecture and the pathogenesis of diseases like cancer and neurodegenerative disorders. Anti-β Tubulin antibody (3F3-G2) is recommended for researchers investigating the intricate architecture and dynamics of the cytoskeleton.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-beta Tubulin Antibody (3F3-G2) has 62 citations in a variety of scientific publications.

Primary antibodies like Anti-beta Tubulin Antibody (3F3-G2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

beta Tubulin Antibody (3F3-G2) Specifications

Alternate Product Name: β Tubulin

Product Clone Name: 3F3-G2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: β Tubulin

Epitope Species: rat

Product Reactivity/Detection: all vertebrate forms of β Tubulin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 62 citations in various scientific publications

Available Conjugates/Forms for beta Tubulin Antibody (3F3-G2): N/A

The preferred beta Tubulin antibody is beta Tubulin Antibody (D-10): sc-5274.