Benztropine mesylate CAS: 132-17-2
MF: C21H25NO•CH4SO3
MW: 403.53
An antagonist of the mAChR.

Benztropine mesylate (CAS 132-17-2)

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Alternate Names: Benztropine methanesulfonate
Application Benztropine mesylate is an antagonist of the mAChR
CAS 등록번호: 132-17-2
순도: ≥98%
분자량: 403.53
분자식: C21H25NO•CH4SO3
추가 정보: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* 참조분석증명서대량의 측정 데이터(함수량포함).

Benztropine mesylate is a derivative of Atropine (sc-203322) and an antagonist of the mAChR (muscarinic acetylcholine receptor). This compound demonstrates anti-muscarinic effects comparable to Atropine, and also demonstrates competitive anti-nicotinic action at the nAChR (nicotinic acetylcholine receptor) unobserved with Atropine.


References

1. Bowers, M.B. and Roth, R.H. 1972. Br. J. Pharmacol. 44: 301-306. PMID: 4148918
2. Gao, Z.G., et al. 1998. J. Pharm. Pharmacol. 50: 1299-1305. PMID: 9877318

Physical State :
Solid
용해도 :
Soluble in water (81 mg/ml at 25° C), DMSO (50 mg/ml at 25° C), ethanol (81 mg/ml at 25° C), and ether (very slightly).
저장 :
Store at 4° C
녹는점 :
135° C (lit.)
IC50 :
dopamine transporter: IC50 = 118 nM; MTSET-induced inhibition of [3H]WIN binding to Wild-type dopamine transporter : EC5050 = 28 µM
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
RTECS :
YM3150000
PubChem CID :
Merck Index :
14: 1121
MDL Number :
MFCD00074784
EC Number :
205-048-8
SMILES :
CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4.CS(=O)(=O)O

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