Astrovirus Antibody (8E7): sc-53559
- Astrovirus Antibody (8E7) is a mouse monoclonal IgG1 κ Astrovirus antibody, cited in 4 publications, provided at 200 µg/ml
- raised against purified astrovirus type 2
- Astrovirus Antibody (8E7) is recommended for detection of Astrovirus by IP; may cross-react with all five known serotypes of astrovirus
- Anti-Astrovirus Antibody (8E7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Astrovirus Antibody (8E7). This reagent is now offered in a bundle with Astrovirus Antibody (8E7) (see ordering information below).
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Astrovirus Antibody (8E7) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Astrovirus protein of Astrovirus origin by immunoprecipitation (IP). Anti-Astrovirus antibody (8E7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. Astroviruses, which belong to the Astroviridae family, are small, spherical viruses measuring approximately 28 nm in diameter, characterized by their distinctive star-like appearance under an electron microscope. These viruses have been classified into eight human species, from human astrovirus (HAstV)-1 to HAstV-8, with HAstV-1 being the most prevalent among the identified serotypes. The positive-sense single-stranded RNA genome of astroviruses is notable for lacking a helicase, a feature that distinguishes them from caliciviruses. Astrovirus infection is primarily associated with gastroenteritis, a mild yet uncomfortable condition characterized by diarrhea, vomiting, and abdominal pain, which typically resolves within a few days. Understanding the structure of Astrovirus is crucial, as this protein plays a significant role in viral infection of host cells and immune response. Astrovirus′s unique structural features facilitate interaction with host cell receptors, making this target important for therapeutic interventions and vaccine development.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Astrovirus Antibody (8E7) References:
- Astrovirus-induced synthesis of nitric oxide contributes to virus control during infection. | Koci, MD., et al. 2004. J Virol. 78: 1564-74. PMID: 14722310
- One-year survey of astrovirus infection in children with gastroenteritis in a large hospital in Hungary: occurrence and genetic analysis of astroviruses. | Jakab, F., et al. 2004. J Med Virol. 74: 71-7. PMID: 15258971
- C-terminal nsP1a protein of human astrovirus colocalizes with the endoplasmic reticulum and viral RNA. | Guix, S., et al. 2004. J Virol. 78: 13627-36. PMID: 15564473
- Human astrovirus C-terminal nsP1a protein is involved in RNA replication. | Guix, S., et al. 2005. Virology. 333: 124-31. PMID: 15708598
- Pathogenesis of astrovirus infection. | Moser, LA. and Schultz-Cherry, S. 2005. Viral Immunol. 18: 4-10. PMID: 15802949
- Identification of structural domains involved in astrovirus capsid biology. | Krishna, NK. 2005. Viral Immunol. 18: 17-26. PMID: 15802951
- Development of a one step real-time RT-PCR method for sensitive detection of human astrovirus. | Royuela, E., et al. 2006. J Virol Methods. 133: 14-9. PMID: 16321452
- Molecular characterization of human astroviruses isolated in Brazil, including the complete sequences of astrovirus genotypes 4 and 5. | Silva, PA., et al. 2006. Arch Virol. 151: 1405-17. PMID: 16421636
- Diagnosis of astrovirus gastroenteritis by antigen detection with monoclonal antibodies. | Herrmann, JE., et al. 1990. J Infect Dis. 161: 226-9. PMID: 2105359
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Astrovirus Antibody (8E7) | sc-53559 | 200 µg/ml | $322.00 | |||
Astrovirus Antibody (8E7): m-IgG Fc BP-HRP Bundle | sc-525606 | 200 µg Ab; 10 µg BP | $361.00 | |||
Astrovirus Antibody (8E7) AC | sc-53559 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Astrovirus Antibody (8E7) HRP | sc-53559 HRP | 200 µg/ml | $322.00 | |||
Astrovirus Antibody (8E7) FITC | sc-53559 FITC | 200 µg/ml | $336.00 | |||
Astrovirus Antibody (8E7) PE | sc-53559 PE | 200 µg/ml | $349.00 | |||
Astrovirus Antibody (8E7) Alexa Fluor® 488 | sc-53559 AF488 | 200 µg/ml | $364.00 | |||
Astrovirus Antibody (8E7) Alexa Fluor® 546 | sc-53559 AF546 | 200 µg/ml | $364.00 | |||
Astrovirus Antibody (8E7) Alexa Fluor® 594 | sc-53559 AF594 | 200 µg/ml | $364.00 | |||
Astrovirus Antibody (8E7) Alexa Fluor® 647 | sc-53559 AF647 | 200 µg/ml | $364.00 | |||
Astrovirus Antibody (8E7) Alexa Fluor® 680 | sc-53559 AF680 | 200 µg/ml | $364.00 | |||
Astrovirus Antibody (8E7) Alexa Fluor® 790 | sc-53559 AF790 | 200 µg/ml | $364.00 |