Date published: 2025-9-9

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apolipoprotein E/apoE 항체 (WU E-4): sc-53570

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데이터 시트
  • apolipoprotein E/apoE 항체(WU E-4) 는 마우스 monoclonal IgG1κ, 13간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • human 기원의 B 도메인 결손 재조합체 apoE에 대해 양성 반응이 나타난 A3 도메인에 대한 에피토프 매핑
  • 안티-apolipoprotein E/apoE 항체 (WU E-4)는 WB, IP, IF and IHC(P)으로 mouse, rat and human유래의 apoE 를 감지하는 데에 추천한다.
  • 항-apolipoprotein E/apoE 항체(WU E-4)는 IP용 agarose와 결합되어 이용 가능하며, WB, IHC(P), ELISA용 HRP와 결합되어 이용 가능하며, IF, IHC(P), FCM용 phycoerythrin 또는 FITC와 결합되어 이용 가능합니다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • apolipoprotein E/apoE (WU E-4): sc-53570무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 는 apolipoprotein E/apoE 항체 (WU E-4) 가 WB and IHC(P) 에 응용될 때 우선으로 사용하는 이차 항체 검사 시약입니다.이 시약은apolipoprotein E/apoE 항체(WU E-4) 와 세트로 제공드립니다. (아래의 주문 정보를 참고해 주시길 바랍니다)

빠른 링크

더보기

apoE 항체(WU E-4)는 인간, 마우스 및 쥐의 아포지단백질 E(apoE)를 특이적으로 표적으로 하는 마우스 단일 클론 IgG1 카파 경쇄 항체입니다. 아포지단백 E는 지질 수송과 대사를 매개하는 세포막과 세포질을 포함한 다양한 세포 위치에서 발견되는 중요한 단백질로, 지질 수송과 대사를 매개합니다. 혈장 지단백질에 존재하는 apoE는 지단백질 입자의 결합, 내재화 및 분해에 중요하며, 콜레스테롤과 지질 항상성에 필수적인 역할을 합니다. LDL 수용체 및 간 apoE 수용체와 같은 수용체의 리간드로서, apoE는 콜레스테롤이 풍부한 지단백질의 제거를 촉진하여 심혈관 건강에 영향을 미칩니다. apoE는 간과 뇌를 포함한 여러 기관에서 합성되며, VLDL과 HDL을 포함한 여러 지단백질 분획에 존재합니다. 중요한 것은 apoE가 지질 대사와 신경 퇴행성 질환 모두에 기능적 영향을 미치는 다양한 동형체, 특히 E2, E3, E4와 관련이 있다는 점입니다. apoE(WU E-4) 항체는 웨스턴 블롯팅(WB), 면역 침전(IP), 면역 형광(IF), 파라핀 내장 섹션을 이용한 면역 조직 화학(IHCP) 등의 응용 분야에 권장되며 연구자들에게 지질 수송 및 세포 신호에서 apoE의 역할을 연구할 수 있는 신뢰할 수 있는 도구를 제공합니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

LI-COR®와 Odyssey®는 LI-COR Biosciences의 등록 상표입니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

apolipoprotein E/apoE 항체 (WU E-4)

sc-53570
200 µg/ml
$316.00

apolipoprotein E/apoE (WU E-4): m-IgG Fc BP-HRP 번들

sc-526828
200 µg Ab; 10 µg BP
$354.00

apolipoprotein E/apoE (WU E-4): m-IgG1 BP-HRP 번들

sc-532201
200 µg Ab; 20 µg BP
$354.00

apolipoprotein E/apoE 항체 (WU E-4) AC

sc-53570 AC
500 µg/ml, 25% agarose
$416.00

apolipoprotein E/apoE 항체 (WU E-4) HRP

sc-53570 HRP
200 µg/ml
$316.00

apolipoprotein E/apoE 항체 (WU E-4) FITC

sc-53570 FITC
200 µg/ml
$330.00

apolipoprotein E/apoE 항체 (WU E-4) PE

sc-53570 PE
200 µg/ml
$343.00

apolipoprotein E/apoE 항체 (WU E-4) Alexa Fluor® 488

sc-53570 AF488
200 µg/ml
$357.00

apolipoprotein E/apoE 항체 (WU E-4) Alexa Fluor® 546

sc-53570 AF546
200 µg/ml
$357.00

apolipoprotein E/apoE 항체 (WU E-4) Alexa Fluor® 594

sc-53570 AF594
200 µg/ml
$357.00

apolipoprotein E/apoE 항체 (WU E-4) Alexa Fluor® 647

sc-53570 AF647
200 µg/ml
$357.00

apolipoprotein E/apoE 항체 (WU E-4) Alexa Fluor® 680

sc-53570 AF680
200 µg/ml
$357.00

apolipoprotein E/apoE 항체 (WU E-4) Alexa Fluor® 790

sc-53570 AF790
200 µg/ml
$357.00

Can this antibody work for immunoprecipitation (IP)?

Asked by: leo123
-thank you for your question. Anti-apolipoprotein E/apoE Antibody (WU E-4) is recommended for detection of apoE of mouse, rat and human origin by immunoprecipitation as well as WB, IF and IHC(P)
Answered by: Tech Support Europe
Date published: 2025-05-09

Which APOE epitope is recognized by this antibody (WU E-4)?

Asked by: Suzie
Thank you for your question. The exact epitope for this monoclonal antibody has not yet been epitope mapped, so we do not have this information. It was raised against purified human ApoE of human origin. Please contact our Technical Service Department and we would be glad to discuss the reactivity of this antibody. You can reach us by email at scbt@scbt.com, or use the live chat on our website.
Answered by: Tech Service
Date published: 2017-06-13

Was bedeutet FL bei der Beschreibung des Epitops für diesen AK?

Asked by: Suzie
Vielen Dank für Ihre Anfrage und Ihr Interesse an diesem Produkt. Der apoE Antikörper (WU E-4): sc-53570 wurde gegen das humane ApoE Volllängeprotein gezogen. Die Bezeichnung FL steht in diesem Fall für "full length". Für weitere Informationen wenden Sie sich bitte an unseren Technischen Service in unserem Europäischen Supportbüro in Heidelberg. Sie erreichen uns telefonisch unter 06221 4503 0, per email an: europe@scbt.com oder per Live-Chat auf unserer Webseite www.scbt.com Wir freuen uns Ihnen weiterzuhelfen.
Answered by: Technical Support Europe
Date published: 2017-05-18

What is the recommended starting dilution for immunostaining with apoE (WU E-4): sc-53570 monoclonal antibody?

Asked by: jenniferc
Thank you for your question. The recommended starting dilution for immunostaining is 1:50 with a dilution range of 1:50-1:500. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page. If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Technical Support 5
Date published: 2017-01-20
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Rated 5 out of 5 by from ApoE antibody for western blot application.The antibody worked as described. Price is reasonable. Shipment is fast.
Date published: 2025-02-28
Rated 5 out of 5 by from Excellent detection of apoE by WB and ICCThis antibody showed excellent signal for all three major isoforms of apoE by WB and ICC in murine, rodent and human cell lines. It appears to be specific for the N-terminus of apoE (confirmed by western blotting data using cell lines overexpressing truncated variants of apoE protein).
Date published: 2018-04-06
Rated 4 out of 5 by from Detection by Western BlotClean signal for endogenous ApoE from HepG2 cells as well as recombinant ApoE down to 5 ng.
Date published: 2018-04-05
Rated 5 out of 5 by from Wow !! Superb productOutstanding product for both western blot and IHC staining applications
Date published: 2017-02-04
Rated 5 out of 5 by from Reliable and specificThis antibody is great for Western blot detection of apoE, nice strong bands every time!
Date published: 2016-12-21
Rated 4 out of 5 by from Produced great immunoperoxidase cytoplasmicProduced great immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human testis tissue. -SCBT QC
Date published: 2015-05-12
Rated 5 out of 5 by from Works well for WB with Hep G2 whole cell lysateWorks well for WB with Hep G2 whole cell lysate. -SCBT QC
Date published: 2015-05-06
Rated 5 out of 5 by from Sharp signal obtained in WB with human plateletSharp signal obtained in WB with human platelet extract. -SCBT QC
Date published: 2015-03-10
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apolipoprotein E/apoE 항체 (WU E-4) is rated 4.8 out of 5 by 8.
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