AMD 3465 hexahydrobromide CAS: 185991-07-5
MF: C24H38N6.6HBr
MW: 896.07
A selective and potent CXCR4 antagonist.

AMD 3465 hexahydrobromide (CAS 185991-07-5)

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Alternate Names: N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide
Application AMD 3465 hexahydrobromide is a selective and potent CXCR4 antagonist
CAS 등록번호: 185991-07-5
분자량: 896.07
분자식: C24H38N6.6HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Physical State :
Solid
용해도 :
Soluble in water (50 mM), DMSO (25 mM), DMF (~2.5 mg/ml), and PBS, pH 7.2 (~10 mg/ml).
저장 :
Store at -20° C
굴절률 :
n20D ~1.53 (Predicted)
IC50 :
CXCL12-induced calcium mobilization: IC50 = 4 nM; Cell surface binding of CXCL12: IC50 = 18 nM; Various HIV strains: IC50 = 6-12 nM
Ki 데이타 :
SDF-1α-ligand binding: Ki= 41.7 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9897616
MDL Number :
MFCD20926342
SMILES :
C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3.Br.Br.Br.Br.Br.Br

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