AdoMetDC Antibody (A-8): sc-515656
- AdoMetDC Antibody (A-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 25-41 near the N-terminus of AdoMetDC of human origin
- recommended for detection of AdoMetDC of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for AdoMetDC Antibody (A-8) for WB applications. This reagent is now offered in a bundle with AdoMetDC Antibody (A-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
QUICK LINKS
SEE ALSO...
AdoMetDC Antibody (A-8) is a mouse monoclonal IgG1 antibody that detects AdoMetDC in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AdoMetDC, or adenylmethionine decarboxylase 1, is a crucial enzyme in the polyamine biosynthesis pathway, consisting of 334 amino acids. AdoMetDC monoclonal antibody (A-8) recognizes a protein that plays a vital role in cellular growth and proliferation by catalyzing the conversion of S-adenosyl-L-methionine into biologically active polyamines, which are essential for various cellular functions, including gene regulation and cell signaling. The importance of AdoMetDC extends beyond enzymatic activity; AdoMetDC is synthesized as an inactive proenzyme that undergoes self-maturation to produce two distinct subunits, α and β, which then assemble into an active heterotetramer. This unique structural formation is critical for function, as both the processing of the proenzyme and the catalytic activity of mature AdoMetDC are regulated by polyamines like putrescine, highlighting the intricate balance of cellular processes that depend on this enzyme. Anti-AdoMetDC antibody (A-8) serves as an invaluable tool for researchers studying polyamine metabolism and its implications in cellular growth and tumor promotion.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AdoMetDC Antibody (A-8) | sc-515656 | 200 µg/ml | $322.00 | |||
AdoMetDC Antibody (A-8): m-IgGκ BP-HRP Bundle | sc-525150 | 200 µg Ab, 40 µg BP | $361.00 | |||
AdoMetDC (A-8) Neutralizing Peptide | sc-515656 P | 100 µg/0.5 ml | $69.00 |